<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ritesh Kumar Sharma</style></author><author><style face="normal" font="default" size="100%">Anjana Goel</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Identification of Phytoconstituents in Lawsonia inermis Linn. Leaves Extract by GC-MS and their Antibacterial Potential</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">1</style></keyword><keyword><style  face="normal" font="default" size="100%">4 Napthelenedione</style></keyword><keyword><style  face="normal" font="default" size="100%">Antimicrobial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Lawsone</style></keyword><keyword><style  face="normal" font="default" size="100%">Lawsonia inermis Linn</style></keyword><keyword><style  face="normal" font="default" size="100%">Medicinal plants</style></keyword><keyword><style  face="normal" font="default" size="100%">Methanol extract</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2018</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">1101-1108</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Plant extracts contains multiple active constituents which leads to the production of new drugs from plants and chemicals derived from various parts of plants. The objective of present study was to investigate the GC-MS analysis and antibacterial activity of &lt;em&gt;L. inermis&lt;/em&gt; leaves extracts. &lt;strong&gt;Material and Methods:&lt;/strong&gt; Crude methanol extract and its fractions were tested for the presence of active phytochemicals and GC-MS analysis of hexane; ethyl acetate and aqueous methanol fractions was performed. Antimicrobial activity against six bacterial strain&amp;rsquo;s &lt;em&gt;Escherichia coli, Staphylococcus aureus, Bacillus subtelis, Salmonella typhi, Klebsiella&lt;/em&gt; and &lt;em&gt;Pseudomonas aeruginosa&lt;/em&gt; was also tested. &lt;strong&gt;Results:&lt;/strong&gt; Phytochemical screening of extract confirmed the presence of carbohydrates, glycosides, quinones, steroids and phenol. In GC-MS chromatograms, 56, 108 and 19 peaks were obtained and out of these, 13, 17 and 7 compounds were identified in hexane, ethyl acetate and aqueous methanol fractions, respectively. &lt;strong&gt;Conclusion:&lt;/strong&gt; For best of our knowledge in &lt;em&gt;L.&amp;nbsp;inermis&lt;/em&gt; leaves extract, Celidoniol and Vitamin E has not been reported earlier in hexane fractions. While 2, 3 dihydrobenzo furan, 1-H indole -1, 3 (2H)-dione, 1 (3H)-Isobenzofuranone, 1H Isoindole-1, 3 (2H) Dione, Napthelene, 2 ethoxy, 2 (4H) Benzofuranone, Vitamin E, Benzene, 1 isocyano 4 methyl are also identified for the first time in ethyl acetate fraction. Also, in aq. Methanol fraction 1(3H)-isobenzofuranone, Squalene and Vit E were not previously identified. Highest antibacterial activity was confirmed in crude methanol extract which might be due to all the antibacterial compounds present in its fractions. The present study helped in identifying phytoconstituents present in the extract and its fractions which are responsible for various biological and antibacterial activities.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">xx1101</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Ritesh Kumar Sharma&lt;sup&gt;1,&lt;/sup&gt;*, Anjana Goel&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Ph.D. Scholar, Department of Biotechnology, IAH, GLA University, Mathura, Uttar Pradesh, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Associate Professor, Department of Biotechnology, IAH, GLA University, Mathura, Uttar Pradesh, INDIA.&lt;/p&gt;</style></auth-address></record></records></xml>