<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Richa Gupta</style></author><author><style face="normal" font="default" size="100%">Ghanshyam Das Gupta</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Formulation Development and Evaluation of Anti-inflammatory Potential of Cordia obliqua Topical Gel on Animal Model</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Carbopol 940</style></keyword><keyword><style  face="normal" font="default" size="100%">Carrageenan induced edema</style></keyword><keyword><style  face="normal" font="default" size="100%">Cordia</style></keyword><keyword><style  face="normal" font="default" size="100%">in-vitro diffusion</style></keyword><keyword><style  face="normal" font="default" size="100%">Topical gel</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/388</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">s93-s98</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; The plants of genus &lt;em&gt;Cordia&lt;/em&gt; has been used in traditional medicine for many diseases from history. &lt;em&gt;Cordia obliqua&lt;/em&gt; Willd. is also a medicinally important plant and it has been proved by modern scientific research. &lt;strong&gt;Objective:&lt;/strong&gt; This study is aimed to formulate and characterize a topical gel from &lt;em&gt;Cordia obliqua&lt;/em&gt; leaf methanol extract and evaluate its effect on carrageenan induced rat paw edema. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; The methanol extract was prepared by successive solvent extraction using soxhlet apparatus. Topical gel was designed to prepare by Dispersion method using Carbopol 940 as polymer. The various gel characteristics was studied by standard procedures like Homogeneity, grittiness, extrudability, drug content, spread ability and &lt;em&gt;in-vitro&lt;/em&gt; diffusion study. The anti-inflammatory potential of gel was evaluated by Carrageenan induced rat paw edema method in comparison with standard Diclofenac Sodium gel 1% on Albino rats. &lt;strong&gt;Results:&lt;/strong&gt; The herbal gel was found homogeneous with good extrudability, no grittiness, pH 6.79 and drug content 93.167%. The anti-inflammatory activity of herbal gel was found comparable with standard Diclofenac Sodium gel and has shown 82.71% edema inhibition after 4 h of treatment. &lt;strong&gt;Conclusion:&lt;/strong&gt; &lt;em&gt;Cordia obliqua&lt;/em&gt; gel was found suitable as a standard topical gel formulation and it can be used safely for treatment of edema.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">s93</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Richa Gupta&lt;sup&gt;1&lt;/sup&gt;*, Ghanshyam Das Gupta&lt;sup&gt;2 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Assistant Professor, Department of Pharmacognosy, ASBASJSM College of Pharmacy, Bela (Ropar), 140111, Punjab and PhD scholar of IK Gujral Punjab Technical University, Jalandhar, Punjab, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Director &amp;amp; Professor, Department of Pharmaceutics, ISF College of Pharmacy, Ghal Kalan, Ferozpur G. T. road, Moga, 142001, Punjab, INDIA.&lt;/p&gt;</style></auth-address></record></records></xml>