<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ngurzampuii Sailo</style></author><author><style face="normal" font="default" size="100%">Zonunmawii Z</style></author><author><style face="normal" font="default" size="100%">Simran Kaur</style></author><author><style face="normal" font="default" size="100%">Chinmoyee Borah</style></author><author><style face="normal" font="default" size="100%">Dhritiman Roy</style></author><author><style face="normal" font="default" size="100%">Bibhuti Bhusan Kakoti</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Pharmacognostic Standardization, Phytochemical Profiling, Antioxidant Activity, and Toxicological Evaluation of the Traditionally Used Medicinal Plant Prunus wallichii Steud.</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Acute toxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">HPTLC</style></keyword><keyword><style  face="normal" font="default" size="100%">Pharmacognostic standardization</style></keyword><keyword><style  face="normal" font="default" size="100%">Physicochemical</style></keyword><keyword><style  face="normal" font="default" size="100%">Prunus wallichii Steud</style></keyword><keyword><style  face="normal" font="default" size="100%">Sub-acute toxicity</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2026</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2026</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">18</style></volume><pages><style face="normal" font="default" size="100%">187-200</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Traditional medicinal plants play a crucial role in the management of several diseases and serve as a valuable source of bioactive compounds having significant therapeutic properties. &lt;em&gt;Prunus wallichii&lt;/em&gt; Steud., a medicinal plant traditionally used by the Mizo tribe, remains unexplored despite its ethnomedicinal importance. &lt;strong&gt;Objective: &lt;/strong&gt;The present study aimed to investigate the pharmacognostic characteristics, phytochemical profile, antioxidant potential, and safety evaluation of &lt;em&gt;P. wallichii&lt;/em&gt;. &lt;strong&gt;Methods:&lt;/strong&gt; The study investigates the pharmacognostic standardization, total phenolic and total flavonoid content, in vitro antioxidant activity, acute and sub-acute toxicity studies of extracts, and HPTLC qualitative analysis of methanolic extract. &lt;strong&gt;Results:&lt;/strong&gt; Pharmacognostic standardization established the identity, purity, and quality of the crude drug. The methanolic extract exhibited higher total phenolic content (207.13 ± 2.041 mg GAE/g) and total flavonoid content (539.99 ± 25.23 mg QE/g) compared to the hydro-ethanolic extract (156.16 ± 6.55 mg GAE/g and 333.33 ± 24.035 mg QE/g, respectively). Both extracts demonstrated significant dose-dependent antioxidant activity in hydroxyl radical and hydrogen peroxide scavenging assays. Acute and sub-acute toxicity studies in rodents revealed the LD&lt;sub&gt;50&lt;/sub&gt; was greater than 2000 mg/ kg showing no adverse toxic effects and mortality during the study period. Hematological, biochemical, and histopathological studies demonstrated the safety profile of the extracts. High-performance thin layer chromatography analysis confirmed the presence of two bioactive markers, scopoletin and taxifolin, which are known for their diverse pharmacological activities. &lt;strong&gt;Conclusion:&lt;/strong&gt; The study findings provide scientific evidence supporting the traditional medicinal use of &lt;em&gt;P. wallichii&lt;/em&gt; and highlight its potential for future therapeutic and pharmacological applications.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">187</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Ngurzampuii Sailo&lt;sup&gt;1,2*&lt;/sup&gt;, Zonunmawii&lt;sup&gt;1&lt;/sup&gt;, Simran Kaur&lt;sup&gt;3&lt;/sup&gt;, Chinmoyee Borah&lt;sup&gt;1&lt;/sup&gt;, Dhritiman Roy&lt;sup&gt;1&lt;/sup&gt;, Bibhuti Bhusan Kakoti&lt;sup&gt;1,3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmaceutical Sciences, Faculty of Science and Engineering, Dibrugarh University, Dibrugarh, Assam, 786004, INDIA&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;NEF College of Pharmacy, Sawkuchi, Guwahati, Assam, 781040, INDIA&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Centre for Biotechnology and Bioinformatics, Dibrugarh University, Dibrugarh, Assam, 786004, INDIA&lt;/p&gt;
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