<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Pornpun Laovachirasuwan</style></author><author><style face="normal" font="default" size="100%">Sonesay Thammavong</style></author><author><style face="normal" font="default" size="100%">Khwanruan Naksuwankul</style></author><author><style face="normal" font="default" size="100%">Sounantha suvanlasy</style></author><author><style face="normal" font="default" size="100%">Theera Rittirod</style></author><author><style face="normal" font="default" size="100%">Weerapong Prasongchean</style></author><author><style face="normal" font="default" size="100%">Jidapha Sangmahachai</style></author><author><style face="normal" font="default" size="100%">Sutthipong Chiangtong</style></author><author><style face="normal" font="default" size="100%">Panwad Lerdpiriyasakulkit</style></author><author><style face="normal" font="default" size="100%">Burin T. Sriwong</style></author><author><style face="normal" font="default" size="100%">Piyachet Jatuten</style></author><author><style face="normal" font="default" size="100%">Methin Phadungkit</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Total Phenolic and Flavonoid Contents, Antioxidant and Antiinflammatory Activities of Phellinus rimosus Extracts</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-inflammatory activity</style></keyword><keyword><style  face="normal" font="default" size="100%">antioxidant activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Flavonoid content</style></keyword><keyword><style  face="normal" font="default" size="100%">nitric oxide inhibition</style></keyword><keyword><style  face="normal" font="default" size="100%">Phellinus rimosus</style></keyword><keyword><style  face="normal" font="default" size="100%">Phenolic content</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2026</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2026</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">18</style></volume><pages><style face="normal" font="default" size="100%">181-186</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;&lt;em&gt;Phellinus rimosus&lt;/em&gt; is a medicinal mushroom with potential bioactive properties, although scientific evidence supporting its pharmacological activities remains limited.&lt;strong&gt; Objective: &lt;/strong&gt;To investigate the phenolic and flavonoid contents, antioxidant capacity, and anti-inflammatory activity of ethanolic and aqueous extracts of &lt;em&gt;P. rimosus&lt;/em&gt;. &lt;strong&gt;Materials and Methods: &lt;/strong&gt;Total phenolic content (TPC) and total flavonoid content (TFC) were determined using colorimetric assays. Antioxidant activity was evaluated by DPPH, ABTS, and FRAP methods. Anti-inflammatory activity was assessed by measuring nitric oxide (NO) inhibition in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages. Statistical analysis was performed at P &amp;lt; 0.05. &lt;strong&gt;Results: &lt;/strong&gt;The ethanolic extract contained significantly higher TPC (361.04 ± 5.69 mg GAE/g extract) and TFC (646.55 ± 6.29 mg RE/g extract) than the aqueous extract. It exhibited strong antioxidant activity with IC&lt;sub&gt;₅₀&lt;/sub&gt; values of 9.56 ± 0.47 μg/mL (DPPH) and 5.40 ± 0.06 μg/mL (ABTS), and a FRAP value of 52.39 ± 0.25 mM Fe&lt;sup&gt;²⁺&lt;/sup&gt;/100 mg extract. The ethanolic extract also significantly inhibited NO production (IC&lt;sub&gt;₅₀&lt;/sub&gt; = 54.40 ± 2.35 μg/mL) without cytotoxicity, whereas the aqueous extract showed no inhibitory effect. &lt;strong&gt;Conclusion:&lt;/strong&gt; The ethanolic extract of&lt;em&gt; P. rimosus&lt;/em&gt; demonstrates notable antioxidant and anti-inflammatory activities and may serve as a promising natural source of bioactive compounds.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">181</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Pornpun Laovachirasuwan&lt;sup&gt;1&lt;/sup&gt;, Sonesay Thammavong&lt;sup&gt;2&lt;/sup&gt;, Khwanruan Naksuwankul&lt;sup&gt;3&lt;/sup&gt;, Sounantha suvanlasy&lt;sup&gt;2&lt;/sup&gt;, Theera Rittirod&lt;sup&gt;4&lt;/sup&gt;, Weerapong Prasongchean&lt;sup&gt;4&lt;/sup&gt;, Jidapha Sangmahachai&lt;sup&gt;4&lt;/sup&gt;, Sutthipong Chiangtong&lt;sup&gt;4&lt;/sup&gt;, Panwad Lerdpiriyasakulkit&lt;sup&gt;4&lt;/sup&gt;, Burin T. Sriwong&lt;sup&gt;5&lt;/sup&gt;, Piyachet Jatuten&lt;sup&gt;6&lt;/sup&gt;, Methin Phadungkit&lt;sup&gt;4*&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Pharmacy, Mahasarakham University, THAILAND.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Faculty of Pharmacy, University of Health Sciences, LAOS PDR.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Faculty of Science, Mahasarakham University, THAILAND.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Faculty of Pharmacy, Nakhonratchasima College, THAILAND.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Faculty of Pharmacy, Silpakorn University, THAILAND.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Moryathai 101 Co., Ltd., THAILAND.&lt;/p&gt;
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