<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Anu Avudaiappan</style></author><author><style face="normal" font="default" size="100%">Krittika Chandran</style></author><author><style face="normal" font="default" size="100%">Sajna Keeyari Purayil</style></author><author><style face="normal" font="default" size="100%">Abiramy Krishnan</style></author><author><style face="normal" font="default" size="100%">Maimuna Gai</style></author><author><style face="normal" font="default" size="100%">Aishath Aala Rasheed</style></author><author><style face="normal" font="default" size="100%">Soh Lee May</style></author><author><style face="normal" font="default" size="100%">Nur Izzah Bt Tohar</style></author><author><style face="normal" font="default" size="100%">Jamal Moideen Muthu Mohamed</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Green-Synthesized Copper Nanoparticles from Azadirachta Indica for Antimicrobial Applications and Potential Visible-Light- Assisted Organic Load Reduction of POME</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antimicrobial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Azadirachta indica</style></keyword><keyword><style  face="normal" font="default" size="100%">Copper nanoparticles</style></keyword><keyword><style  face="normal" font="default" size="100%">Disinfection</style></keyword><keyword><style  face="normal" font="default" size="100%">Green synthesis</style></keyword><keyword><style  face="normal" font="default" size="100%">Wastewater treatment</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2026</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2026</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">18</style></volume><pages><style face="normal" font="default" size="100%">129-138</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Objective: &lt;/strong&gt;Palm Oil Mill Effluent (POME) is a high-strength agro-industrial wastewater of serious environmental concern due to its high organic load and microbial contamination. &lt;strong&gt;Methods:&lt;/strong&gt; Copper nanoparticles (CuNPs) were synthesized using &lt;em&gt;Azadirachta indica&lt;/em&gt; (neem) leaf extract and copper sulfate at different extract-to-metal salt ratios (1:1 and 2:1). The formation of CuNPs was confirmed by color change, FESEM, and EDX analyses. POME samples were collected from two treatment stages (raw and acidification ponds), and bacteria were isolated and identified using morphological, Gram staining, and biochemical tests. The antimicrobial activity of CuNPs at two concentrations (0.008 g and 0.016 g) was evaluated against isolated bacterial strains (&lt;em&gt;Bacillus &lt;/em&gt;spp., Pseudomonas spp., and Stenotrophomonas spp.) using the agar well diffusion method. &lt;strong&gt;Results: &lt;/strong&gt;The synthesized CuNPs ranged from 11–40 nm in size, confirming the presence of elemental copper with bioorganic capping. Antibacterial activity increased with CuNP loading, with the maximum inhibition zone (50 mm) observed for &lt;em&gt;Bacillus &lt;/em&gt;spp. using CuNPs synthesized from a 0.1 M precursor solution and 0.016 g nanoparticle dose. At higher precursor concentrations (1.0 M), aggregation of nanoparticles occurred, leading to reduced antibacterial efficiency. Neem-CuNPs therefore demonstrated strong antimicrobial (disinfection) activity, while photocatalytic effects were observed as a secondary, light-assisted reduction of organic content rather than direct biodegradation. &lt;strong&gt;Conclusion:&lt;/strong&gt; The green-synthesized CuNPs offer an eco-friendly and effective antimicrobial strategy for managing POME-associated bacteria. These findings provide a basis for future work combining CuNPs with biological systems to enhance wastewater remediation.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">129</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Anu Avudaiappan&lt;sup&gt;1&lt;/sup&gt;, Krittika Chandran&lt;sup&gt;1&lt;/sup&gt;, Sajna Keeyari Purayil&lt;sup&gt;1&lt;/sup&gt;, Abiramy Krishnan&lt;sup&gt;1&lt;/sup&gt;, Maimuna Gai&lt;sup&gt;1&lt;/sup&gt;, Aishath Aala Rasheed&lt;sup&gt;1&lt;/sup&gt;, Soh Lee May&lt;sup&gt;1&lt;/sup&gt;, Nur Izzah Bt Tohar&lt;sup&gt;1&lt;/sup&gt;, Jamal Moideen Muthu Mohamed&lt;sup&gt;2*&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Pharmacy &amp;amp; BioMedical Sciences, MAHSA University, Bandar Saujana Putra, 42610 Jenjarom, Selangor, MALAYSIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacology, Faculty of Medicine, Manipal University College Malaysia, Jalan Batu Hampar, Bukit Baru, 75150 Melaka, MALAYSIA.&lt;/p&gt;
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