<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Guntupalli Chakravarthi</style></author><author><style face="normal" font="default" size="100%">Alavala Rajasekhar Reddy</style></author><author><style face="normal" font="default" size="100%">Maddi Ramaiah</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Assessment of Biological Activity and Comparison of UPLC and RP-HPLC Chromatographic Profiles of Clausena excavata Burm.F.</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Angelecin</style></keyword><keyword><style  face="normal" font="default" size="100%">Clausena</style></keyword><keyword><style  face="normal" font="default" size="100%">HPLC</style></keyword><keyword><style  face="normal" font="default" size="100%">Rutaceae</style></keyword><keyword><style  face="normal" font="default" size="100%">UPLC</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://phcogj.com/fulltext/297</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">185-191</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;em&gt;Clausena excavata&lt;/em&gt; Burm. F. (Rutaceae) has long been associated with medicinal benefits in folk medicine, particularly in the treatment of cancer and its related disorders in the eastern region of Thailand. In the the present study Ultra Pressure Liquid Chromatography (UPLC) analysis of methanolic leaf extracts of &lt;em&gt;Clausena excavata&lt;/em&gt; were carried out using short (5 cm &amp;times; 2.1 mm I.D.) columns, containing 2 &lt;em&gt;&amp;mu;&lt;/em&gt;m particles at very high pressures (up to 16000 psi) to obtain high efficiency separations in very short run times. The results indicate that UPLC provided better resolution compared to routine RP-HPLC. The analysis time was drastically reduced (4 min.) which is proved to be a faster and more economical analytical tool than RP-HPLC. In addition to that, the present study also evaluates anti-fungal activity against dermatophytes &lt;em&gt;Trichophyton rubrum&lt;/em&gt; and&lt;em&gt; Trichophyton mentographytes&lt;/em&gt; by using an agar incorporation technique. The anti-fungal activity may be due to the presence of Angelecin and gallic acid in the plant extract.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">185</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Guntupalli Chakravarthi&lt;sup&gt;1&lt;/sup&gt;*, Alavala Rajasekhar Reddy&lt;sup&gt;2&lt;/sup&gt;, Maddi Ramaiah&lt;sup&gt;3 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1,2&lt;/sup&gt;Department of Pharmacy, K L University, Vaddeswaram, Guntur, A. P. India-522502.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Pharmacognosy &amp;amp; Phytochemistry, Hindu College of Pharmacy, Amaravathi Road, Guntur, A.P. India-522002.&lt;/p&gt;</style></auth-address></record></records></xml>