<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Oscar Herrera-Calderon</style></author><author><style face="normal" font="default" size="100%">Wilfredo Bulege-Gutiérrez</style></author><author><style face="normal" font="default" size="100%">Luz Alexandra Javier-Silva</style></author><author><style face="normal" font="default" size="100%">Melva Iparraguirre- Meza</style></author><author><style face="normal" font="default" size="100%">Victor Guillermo Sanchez-Araujo</style></author><author><style face="normal" font="default" size="100%">Elizabeth Julia Melgar-Merino</style></author><author><style face="normal" font="default" size="100%">Johnny Aldo Tinco-Jayo</style></author><author><style face="normal" font="default" size="100%">José Santiago Almeida-Galindo</style></author><author><style face="normal" font="default" size="100%">Josefa Bertha Pari-Olarte</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Tanacetum Parthenium (L.) Sch Bip From Peru: Antioxidant Profile and The Antinociceptive Effect in An Experimental Model</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Analgesic</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Medicinal Plants.</style></keyword><keyword><style  face="normal" font="default" size="100%">Polyphenols</style></keyword><keyword><style  face="normal" font="default" size="100%">Tanacetum parthenium</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">435-437</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;&lt;em&gt;Tanacetum parthenium&lt;/em&gt; (L.) Sch Bip known as “santa maría” (&lt;em&gt;Asteraceae&lt;/em&gt; family) is used in Peru for inflammatory diseases and also in colic, stomachache, headaches, diarrhea, among other. &lt;strong&gt;Objective:&lt;/strong&gt; The aim was to determine the antioxidant profile, and analgesic effect of ethanolic extract of flowers and leaves of &lt;em&gt;T. parthenium &lt;/em&gt;&lt;strong&gt;Material and Methods:&lt;/strong&gt; Leaves and flowers of &lt;em&gt;T. parthenium&lt;/em&gt; were soaked in 96% ethanol and the obtained extract was analyzed using chemical reactions for identifying each secondary metabolite, 2,2-Diphenyl-1-picrylhydrazyl (DPPH) was used to determine the antioxidant capacity, and the antinociceptive effect was determined by using tail flick method.&lt;strong&gt; Results:&lt;/strong&gt; Qualitative phytochemical study indicates the presence phenolic compounds, alkaloids, flavonoids, saponins and steroids in both extracts. In DPPH assay IC&lt;sub&gt;50 &lt;/sub&gt;showed in leaves and flowers extract 452.10 ± 10.2 μg/mL and 270.70 ± 20.6 μg/mL respectively. The antinociceptive effect was better in leaves at doses 300 mg/ Kg than flower extract. &lt;strong&gt;Conclusions:&lt;/strong&gt; The ethanolic extract of flowers of &lt;em&gt;T. parthenium &lt;/em&gt;showed a high antioxidant activity and antinociceptive effect in mice.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">435</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Oscar Herrera-Calderon&lt;sup&gt;1,*&lt;/sup&gt;, Wilfredo Bulege-Gutiérrez&lt;sup&gt;2&lt;/sup&gt;, Luz Alexandra Javier-Silva&lt;sup&gt;3&lt;/sup&gt;, Melva Iparraguirre-Meza&lt;sup&gt;4&lt;/sup&gt;, Victor Guillermo Sanchez-Araujo&lt;sup&gt;5&lt;/sup&gt;, Elizabeth Julia Melgar-Merino&lt;sup&gt;6&lt;/sup&gt;, Johnny Aldo Tinco-Jayo&lt;sup&gt;7&lt;/sup&gt;, José Santiago Almeida-Galindo&lt;sup&gt;8&lt;/sup&gt;, Josefa Bertha Pari-Olarte&lt;sup&gt;9&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacology, Bromatology and Toxicology, Faculty of Pharmacy and Biochemistry, Universidad Nacional Mayor de San Marcos, Lima 15001, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Universidad Continental, Huancayo, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Universidad Privada del Norte, Lima, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Universidad Peruana Los Andes, Huancayo, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Universidad Nacional de Huancavelica, PERU. 6Department of Chemical Sciences, Universidad Nacional San Luis Gonzaga, Ica 11001, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;7&lt;/sup&gt;Department of Human Medicine, Faculty of Health Science, Universidad Nacional de San Cristobal de Huamanga, Ayacucho, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;8&lt;/sup&gt;Department of Basic Sciences, Faculty of Human Medicine, Universidad Nacional San Luis Gonzaga, Ica 11001, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;9&lt;/sup&gt;Department of Chemistry Pharmaceutical, Universidad Nacional San Luis Gonzaga, Ica 11001, PERU.&lt;/p&gt;
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