<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Tarkeshwar Dubey</style></author><author><style face="normal" font="default" size="100%">Kancharla Bhanukiran</style></author><author><style face="normal" font="default" size="100%">Kuna Das</style></author><author><style face="normal" font="default" size="100%">Siva Hemalatha</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Development and Evaluation of Bio fabricated Silver Nanoparticles from Blumea lacera for In-vitro Antibacterial, Antioxidant and Anti-inflammatory Activity</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Green synthesis</style></keyword><keyword><style  face="normal" font="default" size="100%">HPTLC.</style></keyword><keyword><style  face="normal" font="default" size="100%">Inflammation</style></keyword><keyword><style  face="normal" font="default" size="100%">Kukrounda</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytopharmaceuticals</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">266-278</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Increasing prevalence of microbial resistance and side effects of currently available drugs compels the researchers to look for alternate therapies and formulations to overcome this problem. Plant based formulations have been proved to be most reliable agents in recent times. &lt;strong&gt;Objective: &lt;/strong&gt;In the current study, bio fabricated herbal silver nanoparticles (HSNPs) were prepared by reducing silver nitrate (AgNO&lt;sub&gt;3&lt;/sub&gt;) solution with ethyl acetate fractions (EAF) of &lt;em&gt;Blumea lacera &lt;/em&gt;extracts. These bios conjugated HSNPs were then assessed for potential anti-inflammatory and antibacterial activities along with&lt;em&gt; in vitro&lt;/em&gt; antioxidant effect. &lt;strong&gt;Methods and Results: &lt;/strong&gt;The synthesis was confirmed by absorbance peak at 441 nm due to surface plasmon resonance in UV-visible spectrophotometer. FTIR spectra of HSNPs indicated the phytochemicals having C-O bond responsible for reducing of Ag&lt;sup&gt;+&lt;/sup&gt; to Ag&lt;sup&gt;o&lt;/sup&gt;. Average size of HSNPs was found to be 59.21 nm which was in good agreement with TEM and SEM results. EDS analysis showed the existence of Silver, Nitrogen and Carbon in HSNPs. The antibacterial activity of HSNPs in terms of zone of inhibition (ZOI) &lt;em&gt;via&lt;/em&gt; disc diffusion assay and against &lt;em&gt;Staphylococcus aureus&lt;/em&gt; and &lt;em&gt;Escherichia coli &lt;/em&gt;was found to be 25.0±1.19 mm and 18.3±2.08 mm, respectively. The minimum inhibitory concentration (MIC) of HSNPs was found to be 50 μg/ml and 60 μg/ml against S. aureus and E. coli, respectively. The antioxidant capacity of the HSNPs was insignificant as compared to EAF but the results of anti-inflammatory activity was significant (p&amp;lt;0.05).&lt;strong&gt; Conclusion:&lt;/strong&gt; The overall result demonstrated better &lt;em&gt;in-vitro&lt;/em&gt; pharmacological potential of HSNPs compared to neat extract/EAF. Key words: Green synthesis, Phytopharmaceuticals, Inflammation, Kukrounda, HPTLC.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article </style></work-type><section><style face="normal" font="default" size="100%">266</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Tarkeshwar Dubey&lt;sup&gt;1&lt;/sup&gt;, Kancharla Bhanukiran&lt;sup&gt;1&lt;/sup&gt;, Kuna Das&lt;sup&gt;2&lt;/sup&gt;, Siva Hemalatha&lt;sup&gt;1,*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmaceutical Engineering &amp;amp; Technology, Indian Institute of Technology, Banaras Hindu University, Varanasi-221005, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Biotechnology and Medical Engineering, National Institute of Technology, Rourkela, Odisha-769008, INDIA.&lt;/p&gt;
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