<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Resmi Mustarichie</style></author><author><style face="normal" font="default" size="100%">Yoppi Iskandar</style></author><author><style face="normal" font="default" size="100%">Nyi Mekar Saptarini</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Coleus atropurpureus (L) Benth. Leaves as a New Promising Drug for Abscesses Caused by Methicillin-resistant Staphylococcus aureus and Staphylococcus aureus</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antibacterial</style></keyword><keyword><style  face="normal" font="default" size="100%">Coleus atropurpureus (L) Benth.</style></keyword><keyword><style  face="normal" font="default" size="100%">Maceration</style></keyword><keyword><style  face="normal" font="default" size="100%">Methicillin-resistant Staphylococcus aureus (MRSA)</style></keyword><keyword><style  face="normal" font="default" size="100%">Staphylococcus aureus ATTC 25923</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">439-443</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background and Objective:&lt;/strong&gt; Staphylococcus aureus and Methicillin-Resistant Staphylococcus aureus (MRSA) can cause an abscess, a skin condition with a build-up of pus due to a fluid or pus-filled tissue covering. This study aimed to determine the antibacterial activity of the ethanolic extract and its fraction from jawer kotok (Indonesian), &lt;em&gt;Coleus atropurpureus &lt;/em&gt;(L) Benth.) against abscess-causing bacteria, S. aureus and MRSA. &lt;strong&gt;Materials and Methods&lt;/strong&gt;: Laboratory Experimental Design. &lt;em&gt;C. atropurpureus &lt;/em&gt;was collected, macerated using 96% ethanol extract, then fractionated using ethyl acetate and n-hexane. Antibacterial properties of ethanol extract and its fraction using S. aureus ATTC 25923 and MRSA. Statistical analysis used: descriptive statistics. &lt;strong&gt;Results: &lt;/strong&gt;It was found that the MIC values for S. aureus ATTC 25923 and MRSA were in the range of 0.78% - 1.56% w/v and the MBC value for the two test bacteria was 1.56% &lt;strong&gt;Conclusions&lt;/strong&gt;: Ethanol extract and n.hexane fraction from&lt;em&gt; C. atropurpureus&lt;/em&gt; were new drugs for abscess treatment. It is necessary to research the formulation and evaluation of the ethanolic extract and the n-hexane fraction from&lt;em&gt; C. atropurpureus &lt;/em&gt;against the two bacteria that cause abscesses first.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article </style></work-type><section><style face="normal" font="default" size="100%">439</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Resmi Mustarichie&lt;sup&gt;1,*&lt;/sup&gt;, Yoppi Iskandar&lt;sup&gt;2&lt;/sup&gt;, Nyi Mekar Saptarini&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, 45363, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Biology Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, 45363, INDONESIA.&lt;/p&gt;
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