<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Biomechy Oktomalioputri</style></author><author><style face="normal" font="default" size="100%">Meutia Savitri</style></author><author><style face="normal" font="default" size="100%">Dwisari Dillasamola</style></author><author><style face="normal" font="default" size="100%">Noverial</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Myocardium Neutrophil Infiltration in Rat Model with Acute Myocardial Infarction Treated by Ramipril</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">ACE inhibitors</style></keyword><keyword><style  face="normal" font="default" size="100%">Acute Myocardial Infarction (AMI)</style></keyword><keyword><style  face="normal" font="default" size="100%">Neutrophils</style></keyword><keyword><style  face="normal" font="default" size="100%">Ramipril</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">1116-1121</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Acute myocardial infarction (AMI) is a cardiovascular disease that attacks myocardial cells due to long-standing ischemia. In AMI there is neutrophil infiltration associated with the prognosis of the disease. One of the initial therapies for AMI is ACE inhibitors. &lt;strong&gt;Objective: &lt;/strong&gt;To determine myocardial neutrophil infiltration In rat model with acute myocardial infarction which is given ramipril as an Ace inhibitor. &lt;strong&gt;Method:&lt;/strong&gt; This research is an experimental study using the Post Test Only Control Group study design. This study used 24 experimental rats which were divided into 3 treatment groups. Data were analyzed using the One Way ANOVA test and the Least Significant Differences test. &lt;strong&gt;Results: &lt;/strong&gt;The results obtained were the mean number of neutrophils in the K(-) group was 1.83, the K(+) group was 22.67, and the successive treatment group was 4,17. Significant differences were obtained between the K(+) group and the treatment group where the &lt;em&gt;p &lt;/em&gt;value was 0.001 (&lt;em&gt;p &lt;/em&gt;&amp;lt;0.05). &lt;strong&gt;Conclusion:&lt;/strong&gt; There is an effect of 4 mg/kg BW ACE Inhibitor ramipril and on the number of myocardial neutrophils of rats with AMI.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1116</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Biomechy Oktomalioputri&lt;sup&gt;1,&lt;/sup&gt;*, Meutia Savitri&lt;sup&gt;1&lt;/sup&gt;, Dwisari Dillasamola&lt;sup&gt;2&lt;/sup&gt;, Noverial&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Medical Faculty Universitas Andalas, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Pharmacy Faculty Universitas Andalas, INDONESIA.&lt;/p&gt;
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