<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">C.Elanchezhiyan</style></author><author><style face="normal" font="default" size="100%">K.Kumaravel</style></author><author><style face="normal" font="default" size="100%">Ahmad bhat</style></author><author><style face="normal" font="default" size="100%">S.Sethupathy</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Protective role of  Helicteres isora plant extract on plasma and tissue glycoprotein components in streptozotocin induced hyperglycemic rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Diabetes</style></keyword><keyword><style  face="normal" font="default" size="100%">Helicteres isora</style></keyword><keyword><style  face="normal" font="default" size="100%">Plasma Glycoproteins</style></keyword><keyword><style  face="normal" font="default" size="100%">Streptozotocin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2014</style></year><pub-dates><date><style  face="normal" font="default" size="100%">26th May 2014</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">6</style></volume><pages><style face="normal" font="default" size="100%">86-91</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;The present investigation was carried out to evaluate the protective role of &lt;em&gt;Helicteres &lt;/em&gt;isora plant extract on glycoprotein metabolism in streptozotocin (STZ) induced type 2 diabetic rats. &lt;em&gt;Helicteres isora &lt;/em&gt;plant extract was administered orally (200 mg/kg body weight) for 40 days to normal and diabetic rats. The effects of Helicteres isora plant extract on plasma and tissue glycoproteins (hexose, hexosamine, sialic acid and fucose) were determined. The levels of plasma glycoproteins containing hexose, hexosamine, sialic acid and fucose were significantly increased in diabetic rats when compared with normal control rats. There was a significant decrease in the level of sialic acid and elevated levels of hexose, hexosamine and fucose in the liver and kidney of STZ induced diabetic rats. On oral administration of&lt;em&gt; Helicteres&lt;/em&gt; isora plant extract to diabetic rats showed decreased levels of plasma glycoproteins. The level of tissue sialic acid was increased whereas the levels of tissue hexose, hexosamine and fucose were reversed to near normal. The present study indicates that the&lt;em&gt; Helicteres&lt;/em&gt; isora plant extract possesses a significant protective effect on glycoprotein metabolism in addition to its anti-diabetic effect.&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Key words:&lt;/strong&gt;&lt;em&gt;Helicteres &lt;/em&gt;isora, Diabetes, Plasma Glycoproteins, Streptozotocin.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;C Elanchezhiyan&lt;sup&gt;*1&lt;/sup&gt;, K Kumaravel&lt;sup&gt;2&lt;/sup&gt;, Bilal Ahmad Bhat&lt;sup&gt;1&lt;/sup&gt; and S Sethupathy&lt;/strong&gt;&lt;sup&gt;&lt;strong&gt;3&lt;/strong&gt;&lt;/sup&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Zoology, Annamalai University, Annamalainagar-608002, Tamil Nadu, India&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Marine Biotechnology, CAS in Marine Biology, Annamalai University, Parangipettai&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Division of Medical Biochemistry, RMMCH, Annamalai University, Annamalainagar-608002.&lt;/p&gt;</style></auth-address></record></records></xml>