<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Annisa Shabrina</style></author><author><style face="normal" font="default" size="100%">Herman Suryadi</style></author><author><style face="normal" font="default" size="100%">Sutriyo</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Effects of Beta Glucosidase Inhibitor on Cellulase Enzyme Activity for Preparation of Microcrystalline Cellulose from Water Hyacinth (Eichhornia crassipes)</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Charaterization</style></keyword><keyword><style  face="normal" font="default" size="100%">Enzyme hydrolyisis</style></keyword><keyword><style  face="normal" font="default" size="100%">Microcrystalline cellulose</style></keyword><keyword><style  face="normal" font="default" size="100%">Water hyacinth</style></keyword><keyword><style  face="normal" font="default" size="100%">β-glucosidase inhibitor</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">October 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1225-1230</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Objective: &lt;/strong&gt;Microcrystalline cellulose (MCC) was a highly desirable excipient which being used for making tablets with direct compression method in Pharmaceutical manufacture. The purpose of this study was to compare microcrystalline cellulose preparation from water hyacinth powder with and without addition of β-glucosidase inhibitor followed by identification and characterization of the resulting powders. &lt;strong&gt;Methods:&lt;/strong&gt; The study was began with isolation of potential organisms from soils in mangrove followed by extraction of • -glucosidase inhibitor. MCC was prepared through enzymatic hydrolysis of alpha-cellulase with and without addition of beta-glucosidase inhibitor. Identification was done using FTIR, then characterized by organoleptic examination, qualitative analysis, starch test, pH test, Scanning Electron Microscopy (SEM) analysis of particle size and distribution, X-ray Diffraction (XRD), moisture content, loss on drying test, particle density test, flow rate test and angle of repose test compared to microcrystalline cellulose which had been available on the market.&lt;strong&gt; Results: &lt;/strong&gt;The hydrolysis conditions were carried out at 30°C, for 2 h and the powder was dissolved in acetate buffer pH 7 by addition of enzyme and 2.5 ml inhibitor. MCC yield with addition of beta-glucosidase inhibitor (80%) was higher than without addition of beta-glucosidase (68%). &lt;strong&gt;Conclusion: &lt;/strong&gt;Addition of beta glucosidase inhibitor showed positive impact to increase MCC yield from alpha cellulose sample.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1225</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Annisa Shabrina&lt;sup&gt;1&lt;/sup&gt;, Herman Suryadi&lt;sup&gt;1&lt;/sup&gt;,*, Sutriyo&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Laboratory of Microbiology and Biotechnology, Faculty of Pharmacy, Universitas Indo-nesia, Depok 16424, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Laboratory of Pharmaceutical Technology, Faculty of Pharmacy, Universitas Indonesia, Depok 16424, INDONESIA.&lt;/p&gt;
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