TY - JOUR T1 - Chemical Constituents of Dracontomelon Dao (Blanco) Merr. et Rolfe JF - Pharmacognosy Journal Y1 - 2017 A1 - Consolacion Y. Ragasa A1 - Tyson C. Batarra A1 - Julius Leonard A. Vivar A1 - Mariquit M. De Los Reyes A1 - Chien-Chang Shen KW - 3-Alkylphenols KW - Anacardaceae KW - Anacardic Acid KW - B-Sitosteryl Fatty Acid Esters KW - B-Sitosteryl-3β-Glucopyranoside-6’-O-Fatty Acid Esters KW - Cardol KW - Dracontomelon dao (Blanco) merr. Et Rolfe AB -

Introduction: The leaves, twigs and flowers of Dracontomelon dao (Blanco) Merr. et Rolfe, an indigenous Philippine tree were investigated for their chemical constituents. Methods: The compounds were isolated by silica gel chromatography and their structures were identified by NMR spectroscopy. Results: Chemical investigation of D. dao led to the isolation of cardol (1), β-sitosteryl-3β-glucopyranoside-6, O-fatty acid esters (2), β-sitosteryl fatty acid esters (3), and a mixture of β-sitosterol (4a) and stigmasterol (4b) from the petiole; 1, a mixture of 4a and 4b, anacardic acid (5), triacylglycerols (6), monoacylglycerol (7), long-chain fatty acid esters (8), and linoleic acid (9) from the twigs; and a mixture of 4a and 4b, 5, 6, 8, long-chain fatty alcohols (10), and long- chain hydrocatbons (11) from the flowers of D. dao.The structures of 1 and 5 were elucidated by extensive 1D and 2D NMR spectroscopy, while those of 2-4 and 6-11 were identified by NMR spectroscopy. Conclusion: This is the first report on the isolation of 1, 4b and 6-9 from D. dao.

VL - 9 UR - /files/pj-9-5/10.5530pj.2017.5.103/index.html IS - 5 ER -