01969nas a2200229 4500008004100000245011100041210006900152260001900221300001400240490000700254520127900261653001801540653001301558653001801571653002501589100001601614700001801630700001501648700002101663700001601684856003901700 2019 eng d00aChemical Standardization of Thetran Vithai Kutinir Chooranam-An Antidiabetic Siddha Polyherbal Formulation0 aChemical Standardization of Thetran Vithai Kutinir ChooranamAn A cSeptember 2019 a1106-11130 v113 a

Introduction: Belief of general public on herbal drugs led to the stable growth of herbal drug industry thereby necessitated the standardization of herbal drugs and pharmacopoeial standards for their quality control. Aims: Thetran Vithai Kutinir Chooranam (TVKC) is a Siddha polyherbal formulation used for type II diabetes. Aim of the present study is to standardize the drug chemically. Methods and Material: Drug was prepared as per the literature, stored in air tight container and subjected to preliminary phytochemical analysis, physico-chemical, thin layer chromatographic photo documentation, high performance thin layer chromatographic finger printing along with chemical markers such as emodin, chrysophanol and gallic acid, quantitative assay of marker compounds, heavy metal analysis, pesticide residue, aflatoxin and microbial load analysis. Results: The results revealed that the drug contains emodin in minor quantity and gallic acid in considerable quantity. The drug is free from microbial, heavy metal contaminations, aflatoxin and pesticide residues. Conclusion: The derived results could serve as a ready reference for quality control assessment of the drug.

10aAnthraquinone10aKatukkai10aThetranvithai10aVilam Pisin Alkaloid1 aP, Elankani1 aS, Murugammal1 aR, Shakila1 aM, Pitchiahkumar1 a.Kabilan, N uhttps://www.phcogj.com/article/973