02485nas a2200265 4500008004100000245008700041210006900128260001900197300001200216490000700228520172800235653002601963653000901989653001901998100002002017700002002037700002502057700001402082700001702096700001302113700002102126700001602147700001702163856003902180 2019 eng d00aOptimization Method for Determination of Swelling Factor Linum usitatissimum Seeds0 aOptimization Method for Determination of Swelling Factor Linum u cSeptember 2019 a936-9430 v113 a

Aim: Aspire of the investigation is to amend the method for determination of swelling factor of seeds, so it can be determined to optimize the minimum errors which will be reproducible. Swelling factor is play key role if the phytoconsitituent rich in mucilage and polysaccharide which constitute a diverse class of biological macromolecules. Background: Sugar molecules play a broad range of physiochemical properties which are widely used for applications in Pharmacy and the present investigation work is related to determine the effect of parameters such as quantity of seed, volume and nature of solvent, time interval of agitation, time of measurement of result, Effect of quantity of seeds on swelling factor determination. Solvent Optimized technic gives superlative results over IP method. Methods: The swelling factor of Linum usitatissimum was evaluated by using different polar to non-polar solvents by using the standard procedure. During the determination, the role of physical parameter were calculated by comprising the swelling factor with agitation and temperature. Results: According to the observations, the lower concentration levels of swelling index used as an alternative binder to starch. keeping one parameter as variable while all other parameters constant, it was observed that the swelling index of gives better results using the solvents plain distilled water, seeds moistened with alcohol. It was also observed that agitation at every three hours till the process of 24 hours is maintained would give better results, keeping one parameter as variable while all other parameters constant.

10aFormulation parameter10aSeed10aSwelling index1 aDhanalakshmi, S1 aHemalatha, C, N1 aBharathi, Sai, Ramya1 aDhivya, C1 aVanishree, S1 aRekha, V1 aVijayalakshmi, V1 apriya, Hari1 aMonisha, Sai uhttps://www.phcogj.com/article/957