01988nas a2200217 4500008004100000245006400041210006400105260001500169300001000184520135700194653001501551653001101566653002101577653002501598653001101623100002701634700002401661700002201685700002401707856003901731 2019 eng d00aFlavonoids of East Asian Species Serratula manshurica Kitag0 aFlavonoids of East Asian Species Serratula manshurica Kitag cMarch 2019 axx-xx3 a

Aim/ Background: The flavonoid composition of the East Asian species Serratula manshurica Kitag. (Family Asteraceae) growing in the Primorsky Territory, the Amur region and in the South of the Khabarovsk Territory of Russia was studied. Materials and Methods: Flavonoids quercetin-4’-O-β-D-glucuronopyranoside (1) and apigenin-7-O-β-D-glucuronopyranoside (2) were isolated from Serratula manshurica by methods of liquid extraction and recrystallization. The structures of the isolated compounds were identified by UV, NMR spectroscopy and mass spectrometry with electrospray ionization. Separation and quantitative content of flavonoids in the extracts of the aerial part (Leaves, stems, inflorescences) of Serratula manshurica was observed by RP HPLC. Results and Conclusion: The change in the amount of some flavonoids in various phenological phases in the overhead part of Serratula manshurica Kitag was studied. It was revealed that the maximum concentration of flavonoid aglycones in the plant was observed during the before budding in the budding period and their glycosides prevaily in the flowering phase. Widespread across the Far East, Serratula manshurica is promising and renewable source of bioactive compounds.

10aFlavonoids10aLeaves10aNMR spectroscopy10aSerratula manshurica10aSteams1 aV, Myagchilov, Aleksey1 aI, Sokolova, Larisa1 aG, Gorovoy, Peter1 aS, Dmitrenok, Pavel uhttps://www.phcogj.com/article/884