01935nas a2200241 4500008004100000245008400041210006900125260001300194300001200207490000700219520126400226653001701490653001001507653001001517653000901527653001901536653002301555100001901578700001901597700001901616700001901635856003901654 2019 eng d00aEvaluation of Anthelmintic Potential of Leaves and Fruits of Zanthoxylum rhetsa0 aEvaluation of Anthelmintic Potential of Leaves and Fruits of Zan cMay 2019 a475-4780 v113 a

Background: Zanthoxylum rhetsa of family Rutaceae is traditionally employed for treatment of intestinal worms, urinary tract infection, tooth ache, asthma, bronchitis and rheumatism. Thus, the objective of the study was to screen in vitro anthelmintic activity of leaves and fruits of Zanthoxylum rhetsa on Eisenia fetida and Tubifex tubifex. Material and Methods: Total methanol extract and solvent fractions of methanol extract were prepared by maceration and solvent solvent extraction process respectively. The chromatographic fingerprints of total methanol extracts of leaves and fruits were developed using HPTLC. Results: The leaf and fruit extracts showed the presence of alkaloids, flavonoids, terpenoids, coumarins, essential oils and saponins. The extracts exhibited significant anthelmintic activity as evidenced by decrease in paralysis death time in the treatment groups when compared to standard. Conclusion: The results suggest that fruits and leaves of Z rhetsa have promising anthelmintic activity and further studies are required to identify the phytochemicals responsible for anthelmintic activity.

10aAnthelmintic10aFruit10aHPTLC10aLeaf10aPhytochemicals10aZanthoxylum rhetsa1 aMallya, Rashmi1 aMalim, Fehmina1 aNaik, Akanksha1 aBhitre, Milind uhttps://www.phcogj.com/article/858