02749nas a2200241 4500008004100000245018300041210006900224260001800293300001200311490000700323520190500330653002602235653001702261653002402278653002802302653001902330653002402349653002302373653002002396100002902416700002302445856003902468 2019 eng d00aPreparation and Evaluation of Nutraceutical Product Mixture of Seeds of Cucumis melo, Punica granatum, Linum usitatissimum, for Antioxidant, Prebiotic and Nutraceutical Potential0 aPreparation and Evaluation of Nutraceutical Product Mixture of S cFebruary 2019 a383-3870 v113 a

Introduction: Pharmaceutical formulation scientists are currently developing new materials and formulations which vividly include Nutraceuticals. “Nutraceutical” is a substance that is considered a food or part of a food processed as pharmaceutical, which provides medical or health benefits, encompassing prevention and treatment of diseases. Materials and Methods: Under this research Nutraceutical Product Mixture was prepared using seeds of Cucumis melo, Punica granatum and Linum usitatissimum. Individually these three seeds are reported to contain rich nutrients along with antioxidants, probiotic soluble fibres and thus the mixture of three increased this potential. Individual seed and the mixture was evaluated by In- vitro and In-vivo methods for Nutraceutical Potential. Results: Proximate analysis of the mixture showed rich nutrient content and provided good combination of nutrients. Individual seed powder as well as mixture was tested for prebiotic potential using lactobacilli culture, which showed positive results. Each seed powder as well as mixture was tested for antioxidant potential using DPPH free radical scavenging assay, with promising results. It’s in- vivo effect was studied using Wistar albino rat as animal model. This study involved haemogram and lipid profile determination which showed certain promising results. The powder mixture was developed into two products namely capsule and health drink powder formula. Conclusion: The nutraceutical powder mixture of seeds of Cucumis melo, Punica granatum and Linum usitatissimum could be a promising product with antioxidant, prebiotic and nutraceutical potential for diabetic and cardiac patients where oxidative stress is a major underlying cause.

10aAntioxidant potential10aCucumis melo10aLinum usitatissimum10aNutraceutical potential10aNutraceuticals10aPrebiotic potential10aProximate Analysis10aPunica granatum1 aSingh, Meera, Chandradat1 aGujar, Kishore, N. uhttps://www.phcogj.com/article/844