02520nas a2200253 4500008004100000245008700041210006900128260001600197300001200213490000700225520178800232653001602020653002002036653001502056653001102071653002202082653002002104653001902124100002802143700000502171700003102176700002002207856003902227 2018 eng d00aPhysicochemical Standardization of Polyherbal Powder Formulation: Safoof-e-Makhana0 aPhysicochemical Standardization of Polyherbal Powder Formulation cAugust 2018 a899-9060 v103 a

Introduction: Safoof-e-Makhana (SM) is a Unani polyherbal powder formulation used to treat Sexual disorders. Formulation consists of following herbs Orchis latifolia, Hygrophila auriculata, Asparagus racemosus and Elettaria cardamomum. The main aim of this study was to standardize Safoof-e-Makhana (SM), on the basis of organoleptic characters and physico-phytochemical analysis. Methods: The drugs were cleaned, dried in shade and powdered by passing through sieve # no. 80 as per the method described in UPI / National Formulary of Unani Medicine. This Safoof formulation was evaluated using physicochemical tests: powder characterization, extractive value, alcohol and water soluble matter, Ash value, LOD at 1050C, pH and HPTLC fingerprinting. Statistical analysis used: Mean ± SEM. Results: Organoleptic characters of the formulation are light brown colour, characteristic odour, sweet taste and moderately fine texture. Physicochemical parameters displayed water soluble extractive (21.83 ± 0.08), alcohol soluble extractive (7.87 ± 0.09), total ash (4.76 ± 0.08), acid insoluble ash (3.36 ± 0.01), water soluble ash (0.89 ± 0.25), LOD at 105oC (11.38 ± 0.34), pH of 1% and 10% solution were 6.6 ± 0.1 and 6.0 ± 0.1 respectively. Phytochemical qualitative analysis displayed presence of alkaloids, tannins, flavanoids, steroids, terpenoids, carbohydrates, volatile oil. HPTLC fingerprinting data was also set in. Conclusion: The standardization of this formulation was done and the data obtained would be used as a standard for future reference. 

10aFormulation10aPhysicochemical10aPolyherbal10aPowder10aSafoof-e- Makhana10astandardization10aUnani Medicine1 aRather, Gazi, Jahangeer1 a1 aIkram, Shaista, Fatima Moh1 aNaquibuddin, MD uhttps://www.phcogj.com/article/688