02299nas a2200241 4500008004100000245009700041210006900138260001200207300001200219490000600231520159900237653000901836653001701845653002101862653000901883653001001892653002101902100001901923700003001942700002701972700002001999856003802019 2015 eng d00aIron Reducing and Radical Scavenging Activities of 13 Medicinal Plants From Côte d’Ivoire0 aIron Reducing and Radical Scavenging Activities of 13 Medicinal  c01/2015 a266-2700 v73 a

Objective: Oxidative stress has been involved in the development of varied human diseases. The aim of this study was to evaluate the iron reducing power and the antiradical activity of 13 plants traditionally used as medicinal plants in Côte d’Ivoire. Materials and Methods: FRAP (ferric reducing antioxidant power) and ABTS (2,2’-azino-bis(3-ethylbenzothiazoline- 6-sulfonic acid)) assays were used to assess the antioxidant property of 80% methanol extracts prepared from the 13 plants. Results: A high iron reducing activity was exhibited by extracts from leaves of Leea guineensis (42.76 ± 28.54 mg of TE/gdry extract) and Bersama abyssinica (39.77 ± 31.29 mg of TE/g dry extract). Smeathmannia pubescens (% ABTS = 92.44 ± 12.93%), L. guineensis (%ABTS = 89.73 ± 15.10%), Keetia venosa (% ABTS = 88.78 ± 17.36 %) and Sapium ellipticum (%ABTS = 85.86 ± 25.10%), showed promising antiradical activity with IC50 values of 4.50, 5.00, 5.40 and 5.70 μg/mL respectively. These values are (p < 0.05) close to those of Trolox (CI50 = 4.10 μg/mL) and ascorbic acid (CI50 = 4.90 μg/mL). Conclusion: Our findings confirm the traditional use of the studied plants in treatment of various ailments. The results obtained provide promising baseline information for using these medicinal plants for improving the health status of the population.

10aABTS10aAntioxidants10aCôte d’Ivoire10aFRAP10aIron.10aMedicinal plants1 aEvans, Ehouman1 aWitabouna, Koné, Mamidou1 aHonora, Tra, Bi Fézan1 aAdama, Bakayoko uhttps://www.phcogj.com/article/63