01882nas a2200241 4500008004100000245013000041210006900171260001400240300001200254490000700266520114900273653001601422653000901438653001001447653002501457653001901482100002501501700002101526700001701547700001801564700002301582856003501605 2018 eng d00aPharmacognostic and Pharmacological Evaluation of Hyssopus officinalis L. (Lamiaceae) Collected from Kashmir Himalayas, India0 aPharmacognostic and Pharmacological Evaluation of Hyssopus offic cJune 2018 a690-6930 v103 a

Introduction: Hyssopus officinalis L. is a well-known herb for its culinary and medicinal significance. The purpose of this study was to perform the pharmacognostic evaluation. Methods: Physicochemical and phytochemical analysis, HPTLC quantification and in vitro antioxidant and antidiabetic activity were done. Results: Preliminary screening revealed the presence of phytomolecules such as alkaloid (0.99%), tannin (1.75%), sugar (1.96%) and starch (0.68%). Total phenolic and flavonoid content were found to be 2.32% and 1.16% respectively. HPTLC quantification data showed that the content of ferulic acid (0.034%) was higher than caffeic acid (0.0064%) on dry weight basis The IC50 value for the in vitro DPPH radical scavenging assay was 0.50 μg/ml and in vitro anti diabetic assay displayed IC50 value of 0.8366 mg/ml. Conclusion: The study suggests presence of considerable amount of phenolic acids and antioxidant activity in the plant which supports its use in the traditional systems of medicine.

10aAntioxidant10aDPPH10aHPTLC10aHyssopus officinalis10aPhenolic acids1 aSrivastava, Akanksha1 aAwasthi, Kuldeep1 aKumar, Bhanu1 aMisra, Ankita1 aSrivastava, Sharad uhttp://fulltxt.org/article/652