01739nas a2200229 4500008004100000245006800041210006700109260001400176300001200190490000700202520103500209653001601244653002401260653001801284653001801302653001801320653006201338100002301400700002301423700002801446856003501474 2018 eng d00aChemical Constituents of Cymodocea rotundata Asch. and Schweinf0 aChemical Constituents of Cymodocea rotundata Asch and Schweinf cJune 2018 a620-6210 v103 a

Introduction: Cymodocea rotundata Asch. and Schweinf, a widespread seagrass with reported antimicrobial activity, was investigated for its chemical constituents. Methods: The compounds were isolated by silica gel chromatography and identified by NMR spectroscopy. Results: This study has led to the isolation of β-sitosteryl-3β-glucopyranoside-6′-O-fatty acid esters (1), chlorophyll a (2) and a mixture of β-sitosterol (3a) and stigmasterol (3b) in about 1:1 ratio from the dichloromethane extract of C. rotundata. Conclusion: This is the first report on the isolation of 1-3b from C. rotundata. Compounds 2-3b were reported to exhibit antibacterial activity and may be partly responsible for the reported antimicrobial activity of the C. rotundata extract.

10aChlorophyll10aCymodocea rotundata10aCymodoceaceae10aStigmasterol.10aβ-sitosterol10aβ-sitosteryl-3β-glucopyranoside-6′-Ofatty acid esters1 aPerez, Judy, D. V.1 aShen, Chien, Chang1 aRagasa, Consolacion, Y. uhttp://fulltxt.org/article/639