02474nas a2200241 4500008004100000245015500041210006900196260000600265300001000271490000700281520166400288653002701952653002601979653002902005653002102034653002102055653000902076100003002085700002202115700002402137700003202161856003902193 2018 eng d00aEvaluation of Antibacterial Activity of Some Medicinal Plants Extracts Commonly Used in Algerian Traditional Medicine against Some Pathogenic Bacteria0 aEvaluation of Antibacterial Activity of Some Medicinal Plants Ex cx aXX-XX0 v103 a

Introduction: The objective of this study was to evaluate the antibacterial activity of hydromethanolic extracts of Berberis vulgaris, Cassia angustifolia, Cinnamomum cassia, Cistus monspeliensis, Nigella sativa, Punica granatum, Rhus tripartata, Withania frutescens and Zingiber officinale against different Gram-positive and Gram-negative reference bacterial strains. Methods: The evaluation of antibacterial activity for different extracts of each plant was carried out using the disc diffusion method and determination of minimum inhibitory concentration (MIC). Results: The plant extracts showed zone of inhibition ranging from 06.0 to 23.0 mm against one or more tested bacteria, and their efficacy in terms of MICs where ranged from 0.1 to 12.8 mg/mL. The Refluxed and Macerated extracts of these plants have shown relatively similar results in terms of diameters of inhibition and MICs. The extracts of B. vulgaris, C. monspeliensis and P. granatum demonstrated relatively high activity as compared to the other plant extracts mainly against S. aureus, E. faecalis and E. cloacae. Conclusion: Findings of this study indicate that hydromethanolic extracts of these plants have antibacterial activity against the different tested bacterial strains. This activity supports their use in treatment of infections caused by such resistant bacteria.

Key words: Medicinal plants, Hydromethanolic extracts, Antibacterial activity, Inhibition zones, MICs, Bacterial resistance.

10aAntibacterial activity10aBacterial resistance.10aHydromethanolic extracts10aInhibition zones10aMedicinal plants10aMICs1 aBereksi, Mohamed, Senouci1 aHassaïne, Hafida1 aBekhechi, Chahrazed1 aAbdelouahid, Djamel, Eddine uhttps://www.phcogj.com/article/556