02263nas a2200229 4500008004100000245011600041210006900157260001700226300001200243490000700255520157400262653002801836653001201864653002001876653001001896100002101906700002101927700002201948700000501970700002301975856003501998 2018 eng d00aPhysicochemical Analysis of Sumbul-al –Teeb (Nardostachys jatamansi D.C.) Rhizome along with its HPLC Profile0 aPhysicochemical Analysis of Sumbulal Teeb Nardostachys jatamansi cJanuary 2018 a278-2840 v103 a

Introduction: Sumbul-al–Teeb (Nardostachys jatamansi) is a well known traditional medicinal plant used for therapeutic effect in Unani and Ayurvedic System of Medicine. It has been reported to have many therapeutic activities like antifungal, antimicrobial, antioxidant, hepatoprotective and cardioprotective properties. It is also useful in the management of insomnia and CNS disorders. The present study aims towards the evaluation of the parameters involved in the determination of the quality and purity of Nardostachys jatamansi rhizome and its standardization. Methods: Organoleptic characters, extractive values, ash values, phyto-chemical analysis, TLC, fluorescence analysis and HPLC profile etc. were the parameters used for the standardisation of the test drug. Result: Total ash values, water and alcohol soluble extractive values, moisture contents and volatile oil percentage was found to be 7.08%, 3.54%, 2.5%, 8.6% and 02% respectively. TLC profile of N. jatamansi shows 04, 08 and 10 spots in UV short and long wavelength and exposure to iodine vapours respectively. The HPLC pattern shows 34 peaks and the peak no. 01 and 08 are major peaks having area concentration and retention time as 25.974% at 2.8 min. and 29.967% at 4.399 min. respectively. Conclusion: The study will provide referential information for the good quality, purity and identification for the future batches of Nardostachys jatamansi.

10aPhyto-chemical analysis10aQuality10astandardization10aUnani1 aRashid, Mohammad1 aRahman, Aziz, ur1 aAhmad, Qazi, Zaid1 a1 aMian, Syed, Shariq uhttp://fulltxt.org/article/478