01697nas a2200205 4500008004100000245009500041210006900136260001700205300001200222490000700234520109200241653001901333653001301352653001501365653001501380100001701395700001901412700002501431856003501456 2018 eng d00aAntiepileptic Effect of Nux vomica, Homeopathic Remedy, Against Strychnine-Induced Seizers0 aAntiepileptic Effect of Nux vomica Homeopathic Remedy Against St cJanuary 2018 a245-2480 v103 a

Objective: To investigate the antiepileptic effect of homeopathic remedy Nux vomica on mice and its comparison with standard therapeutic diazepam. Methods: BALB-c mice were taken and divided into three groups comprising ten mice in each group. The first group was treated as control; the second group received standard therapeutics (diazepam, i.p.) and the third group received Nux vomica CH7. All groups were treated with strychnine intra peritoneally. Following parameters were observed; start time of convulsions, the number of animals had convulsions, and survival time until death. Results: Nux vomica CH7 homeopathic preparation was found effective in suspending onset of convulsions (P˂ 0.01), and extending survival time until death (P˂ 0.01) in comparison to control mice. It also increased percentage survival in comparison to control as well as diazepam treated animals. Conclusion: Our study demonstrated efficacy of Nux vomica in epilepsy management.

10aAnticonvulsant10aEpilepsy10aNux vomica10aStrychnine1 aGoel, Anjana1 aSaxena, Aditya1 aBhatia, Ashok, Kumar uhttp://fulltxt.org/article/473