01961nas a2200205 4500008004100000245010000041210006900141260001900210300001200229490000600241520127000247653002801517653003301545653003701578653002601615653002801641100002301669700002801692856003501720 2017 eng d00aTotal Phenolic Contents and Free Radical Scavenging Activity of Guaiacum officinale L. Extracts0 aTotal Phenolic Contents and Free Radical Scavenging Activity of  cSeptember 2017 a929-9310 v93 a

Backgound: Guaiacum officinale L. is an alien species to Thailand. It is used as anti-arthritis and anti-rheumatoid agents in Indian folklore medicine. Objective: The present study was aimed to investigate total phenolic contents and free radical scavenging activity of the extracts from Guaiacum officinale L. (Zygophyllaceae). Methods: The plant parts including bark, twig and leaf were extracted using different solvents (ethyl acetate, water and ethanol). Total phenolic contents were determined by Folin-Ciocalteu Colorimetry method while free radical scavenging activity of the extracts was investigated by 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity assay. Results: The results show that the highest total phenolic content is found in the ethyl acetate twig extracts (20.3±0.0031 μg GAE/1 μg extracts). The ethanolic twig extracts had the highest free radical scavenging activity with IC50 of 0.45±0.0188 mg/ml. Conclusion: The extracts from Guaiacum officinale L. exhibit good anti-oxidant activity and may be suitable for development as drugs and supplementary food.

10aEthanolic twig extracts10aEthyl acetate twig extracts.10aFree Radical Scavenging Activity10aGuaiacum Officinale L10aTotal Phenolic Contents1 aManeechai, Suthira1 aPikulthong, Vachiraporn uhttp://fulltxt.org/article/198