02444nas a2200193 4500008004100000245007700041210006900118260001200187300001000199490000600209520185100215653002102066653002602087653002402113653003102137100002402168700002002192856003802212 2015 eng d00aPhytochemical and analytical evaluation of Cordia dichotoma Linn. leaves0 aPhytochemical and analytical evaluation of Cordia dichotoma Linn c01/2015 a58-630 v73 a

Background: An ethnomedicinally important plant, Cordia dichotoma Linn is practiced in various indigenous systems of medicine and popular among the various ethnic groups in India for the cure of variety of ailments as an astringent, anthelmentic, diuretic, demulcent, anti-diabetic and expectorant. Because of the increasing demand, maintaining quality standards is the need of the day. Aims and Objectives: The present study was designed to set standard pharmacognostical, physicochemical, phytochemical, fluorescence and HPTLC chromatographic profile of the leaves of Cordia dichotoma Linn (CD). Materials and Methods: CD, which was previously authenticated, was subjected to pharmacognostical, physicochemical, fluorescence and high performance thin-layer chromatography (HPTLC) analysis as per standard protocol. Results and Conclusion: The final observations were recorded. The loss on drying at 105ºC was found to be 8.5% w/w, total ash value 13% w/w, acid-insoluble ash 5.07% w/w, water-soluble ash 5.49% w/w, water-soluble extractive 9.2% w/w, alcohol-soluble extractive 5.81% w/w and pH (1% aqueous extract) 6.88. Phytochemical screening showed the presence of steroid, carbohydrate, alkaloid, saponin, cardiac glycosides, flavonoid and phenolic compounds in methanolic extract. The CD fluorescence was seen in UV light and it was of different colour in different solvents. HPTLC analysis revealed 5 peaks at wavelength 366 nm with max Rf values in the range of 0.3 to 0.93. The purity and quality of the leaves of Cordia dichotoma or pharmaceutical preparations prepared from it can be tested by pharmacognostical, physicochemical, fluorescence and HPTLC observations of the present study.

10aCordia dichotoma10aFluorescence analysis10aHPTLC chromatogram.10aPhysicochemical parameters1 aRahman, Md., Azizur1 aHussain, Arshad uhttps://www.phcogj.com/article/37