02067nas a2200229 4500008004100000245010500041210006900146260001400215300001200229490000600241520133900247653001401586653001601600653002401616653002801640653003101668100001801699700002201717700002901739700002001768856004901788 2017 eng d00aAntibacterial and Antioxidant Activity of Black Mulberry (Morus nigra L.) Extract for Acne Treatment0 aAntibacterial and Antioxidant Activity of Black Mulberry Morus n cJuly 2017 a611-6140 v93 a

Introduction: Black mulberry is rich in phenols and is hence usable in the treatment of acne. It also contains anthocyanin, a well-known antioxidant. This study aimed to examine the antibacterial and antioxidant properties of black mulberry (Morus nigra L.) extract as a potential raw material for use in beauty care products. Method: Fruit extract was obtained using maceration method with 96% ethanol. The antibacterial activity of the extract was determined by disc diffusion method, while the minimal inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined by microdilution method. Furthermore, the antioxidant activity of the extract was tested by DPPH method. Result: The results showed a 2.5% MIC against S. epidermidis and P. acnes, confirming the antibacterial activity of black mulberry extract. The MBC values for the respective bacterium were 2.5% and 5%. Regarding antioxidant activity, the IC50 value of black mulberry extract was 146.731 mg/mL, suggesting its medium potential. Conclusion: Morus nigra extract has antibacterial activity against S. epidermidis and P. acnes, and has medium potential as antioxidant.

10aAnti acne10aAntioxidant10aMorus Nigra Extract10aPropionibacterium Acnes10aStaphylococcus Epidermidis1 aBudiman, Arif1 aAulifa, Diah, Lia1 aKusuma, Arif, Satria Wir1 aSulastri, Astri u/files/pj-9-5/10.5530pj.2017.5.97/index.html