02273nas a2200205   4500008004100000245010000041210006900141260001900210300001200229490000700241520161700248653002101865653002001886653002401906653001901930653003101949100002701980700002002007856004002027       2025                        eng d00aA Review on Chemical Profile and Pharmacological Properties of Marine Sponge Tectitethya Crypta0 aReview on Chemical Profile and Pharmacological Properties of Mar  cSeptember 2025  a608-6190 v173 a<p class="rtejustify">Marine sponges have gained recognition as a valuable resource due to their significant pharmacological properties. The investigation of substances produced by sponges has been extensively researched to identify their pharmacological properties. Marine sponges, which are part of the phylum Porifera, are thought to be the main source of marine natural products. Sponges are multicellular organisms that have a number of pores and channels for exchanging water; the secondary metabolites they create are in turn influenced by their specific environmental circumstances. Natural products such as lipids, terpenoids, peptides, alkaloids, and steroids are abundant in the marine sponge genus Tectitethya crypta. These compounds have unique chemical structures and have shown promising biological activities, making them ideal candidates for the development of novel drugs to treat various ailments. Tectitethya crypta is a sessile filter-feeder that produces a variety of bioactive compounds, including nucleosides and other secondary metabolites. This article reviews the biology and chemistry of Tectitethya crypta and serves as an introduction to the organism. We discuss the taxonomic classification, morphology, and microenvironment of the sponge, as well as the chemical structures and biological activities of its bioactive compounds. Tectitethya crypta was the source for the development of vidarabine, ara-C, and gemcitabine, which are used to treat viruses and cancer, respectively. We discussed about how these molecules may be used to treat parasitic and infectious disorders.</p>
10aAnticancer drugs10aAntiviral drugs10aBioactive compounds10aMarine sponges10apharmacological properties1 aKondeti, Durga, Prasad1 aSundarrajan, T.  uhttps://www.phcogj.com/article/2546