02356nas a2200229 4500008004100000245009900041210006900140260001800209300001200227490000600239520164600245653002701891653002401918653002001942653002001962653003701982653001302019100001802032700002002050700002102070856003502091 2017 eng d00aComparative Antimicrobial Study of Ethanolic Extract of Leaf and Rhizome of Curcuma longa Linn0 aComparative Antimicrobial Study of Ethanolic Extract of Leaf and cFebruary 2017 a208-2120 v93 a

Introduction: Curcuma longa L., botanically related to ginger belongs to the Zingiberaceae family. It is extensively used in Ayurveda, Unani and Siddha medicine as a home remedy for various diseases. Aim: The present study is to compare the antimicrobial activity of the ethanolic extracts from rhizome and leaf of Curcuma longa Linn. Method: In vitro disc diffusion method and serial dilution method has been used to determine the antimicrobial potency against various bacterial pathogens such as Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus and Bacillus subtilis by comparing the zone of inhibition shown by both the test extracts at different concentration (25 mg/ml, 50 mg/ml, 100 mg/ml, 150 mg/ml, 200 mg/ml, 250 mg/ml, 300 mg/ml) and there MIC value has been evaluated. Ethanol and Ampicillin were used as negative and positive control for the study. Result: The leaf and rhizome extract showed maximum zone of inhibition at 300 mg/ml concentration, which was about 7.6 mm and 8 mm on the bacterial strain Pseudomonas aeruginosa and least effectiveness for other bacterial strain such as Staphylococcus aureus and Bacillus subtilis. The recorded MIC value was at 6.25 mg/ml which showed 3.991% inhibition for rhizome extract and 3.129% inhibition for leaf extract. Conclusion: The rhizome extract was found to be more potent antimicrobial agent than the leaf extract and can be used in future studies.

10aAntibacterial activity10aantimicrobial agent10aBacterial stain10aCurcuma longa L10aMinimum inhibitory concentration10aTurmeric1 aSingh, Nikhil1 aGupta, Sangeeta1 aRathore, Vaibhav uhttp://phcogj.com/fulltext/302