02067nas a2200193 4500008004100000245008400041210006900125260001800194300001200212490000600224520148200230653002001712653001801732653003201750653001801782100001401800700002401814856003501838 2017 eng d00aScreening of Ethanolic Extracts of Medicinal Herbal Drugs Against Oral Microbes0 aScreening of Ethanolic Extracts of Medicinal Herbal Drugs Agains cFebruary 2017 a201-2030 v93 a

Aim: The aim of the present study is to screen the ethanolic extracts of medicinal herbal drugs against oral microbes. Objective: In this study, 3 medicinal herbs were evaluated for antimicrobial activity against five common oral bacteria as a screen for potential candidates for the development of natural antibiotics. Methods: Ethanolic extracts of medicinal herbs were tested for activity against Enterococcus faecalis, Lactobacillus acidophilus, Streptococcus mutans, and Streptococcus sanguis grown in brain heart infusion (BHI) broth. A broth microdilutionassay was used to determine the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). A disk diffusion assay was performed by inoculating bacterial cultures on BHI agar plates with paper disks soaked in each of the medicinal herb extracts. Results: The ethanolic extracts of many of the 3 medicinal herbs showed antimicrobial activity against the five types of pathogenic oral bacteria. The extracts of Caralluma fimbriata, Hemidesmus indicus, and Grape seed effectively inhibited the growth of oral bacteria and showed distinct bactericidal activity. Conclusion: These results suggest that alternative medicines with proven antimicrobial effects, such as Caralluma fimbriata, Hemidesmus indicus, and Grape seed may be useful for the treatment of dental diseases.

10aAnti cariogenic10aDental caries10aNatural products Pathogenic10aOral bacteria1 aL, Harsha1 aThangavelu, Lakshmi uhttp://phcogj.com/fulltext/300