01763nas a2200181 4500008004100000245007400041210006900115260001800184300001400202490000700216520120700223653002501430653001701455653001701472100003101489700002101520856004001541 2024 eng d00aPreeclampsia: A Cardiorenal Syndrome in Obstetric Intensive Care Unit0 aPreeclampsia A Cardiorenal Syndrome in Obstetric Intensive Care  cDecember 2024 a1439-14410 v163 a

Introduction: Cardiorenal syndrome (CRS) encompasses a spectrum of disorders involving heart and kidneys. Preeclampsia and cardiovascular disease are most likely occur via oxidative stress induced endothelial dysfunction. Case presentation: A 34-years-old woman was referred with difficulty of breathing. She had a history of preeclampsia and refractory acute kidney injury (AKI). The patient was diagnosed with severe preeclampsia, partial HELLP syndrome, acute lung edema, cardiomyopathy, CRS, anemia, hyperkalemia, hypoalbuminemia, and AKI. Discussion: CRS and preeclampsia share similar risk factors and mechanisms including pre-existing renal or cardiac disease, diabetes, chronic hypertension, hypertriglyceridemia, obesity, metabolic syndrome, or other systemic disease. She had a history of preeclampsia and refractory AKI. Cardiac dysfunction reduce arterial blood supply and impairs venous return. Renal failure leads to the retention of water and an excessive volume demand. Conclusion: Cardiovascular disorders leading to CRS and preeclampsia remain the leading cause of morbidity in pregnancy.

10aCardiorenal syndrome10aHypertension10aPreeclampsia1 aIzwardy, Mohamad, Evandiar1 aFitriati, Mariza uhttps://www.phcogj.com/article/2446