02720nas a2200265 4500008004100000245010300041210006900144260001700213300001400230490000700244520190000251653002102151653001202172653002702184100003002211700002602241700001602267700001802283700001902301700002902320700002002349700002502369700002002394856004002414 2024 eng d00aTesting the Effectiveness of Anti-Aging Cream Preparations with Snakefish Extract (Channa Striata)0 aTesting the Effectiveness of AntiAging Cream Preparations with S cOctober 2024 a1164-11690 v163 a

Background: Skin aging is caused by dry, rough, scaly, less elastic skin with wrinkles and fold lines. Snakehead fish extract has high antioxidant activity so it can be used as an active ingredient in antiaging cosmetics. Objective: The aim of this research was to see the effectiveness of snakehead fish extract cream as an anti-aging agent. Methods: This research method includes formulating snakehead fish extract cream preparations with various concentrations including: 2.5% (F1), 5% (F2), 7.5% (F3), 10% (F4), evaluating the physical preparations in the form of: organoleptic test, homogeneity test, pH test, stability test, irritation test on volunteer skin, and anti-aging effectiveness test on volunteer skin for 4 weeks with 3 parameter tests, namely water content, pores and wrinkles. Results: The results of the study showed that there were changes that occurred in the volunteers as seen in the measurements of water content, pores and wrinkles on the volunteers' faces. A good increase in changes was found in the F4 formula (10%) in the wrinkle parameter test, namely 26.80%. The number of wrinkles in volunteers from some wrinkles to few wrinkles. The conclusion of this research shows that snakehead fish extract ( Channa striata ) can be formulated in the form of a homogeneous cream dosage with a pH of 5.8 – 6.7, and is stable when stored for 12 weeks at room temperature and does not cause skin irritation. Conclusions: There are differences in the results of each concentration of snakehead fish extract cream in influencing anti-aging effectiveness. The best concentration of 10% snakehead fish extract showed better results compared to other creams in reducing the number of wrinkles on volunteers' facial skin.

10aAnti-Aging Cream10aFormula10aSnakehead Fish Extract1 aHarahap, Cory, Linda Futr1 aHarahap, Hakim, Soleh1 aYanti, Susi1 aSariani, Elmi1 aHadi, Anto, J.1 aRitonga, Nefonavratilova1 aAhmad, Haslinah1 aSani, Hapiz, Arlanda1 aMallongi, Anwar uhttps://www.phcogj.com/article/2401