02418nas a2200193 4500008004100000245010300041210006900144260001700213300001400230490000700244520176900251653004002020653001402060653002802074653001802102100002602120700003802146856004002184 2024 eng d00aClinicopathological Analysis of Mucinous Ovarian Tumors at a Single Center in Indonesia, 2019-20230 aClinicopathological Analysis of Mucinous Ovarian Tumors at a Sin cOctober 2024 a1138-11420 v163 a

Background: Mucinous ovarian tumors are a rare subtype of epithelial ovarian tumors, accounting for approximately 3% of all cases. These tumors exhibit unique clinical and pathological characteristics, with a particularly poor prognosis in advanced stages due to low responsiveness to platinum-based chemotherapy. Objective: This study aims to analyze the relationships between clinicopathological characteristics in patients with mucinous ovarian tumors treated at a single center in Indonesia between 2019 and 2023. Materials and Methods: A correlational study from March to June 2024 analyzed patients with confirmed mucinous ovarian tumors in Indonesia, focusing on age, histopathological grade, FIGO stage, CA-125 levels, tumor size, and metastasis presence. Results: A study of 123 mucinous ovarian tumor patients found that 57.7% were over 40. Histopathological analysis revealed 21.1% were benign, 26% borderline, and 52.8% malignant. Patients over 40 had more malignant tumors, advanced-stage disease, and omental metastasis. A significant correlation was found between malignant histopathology and advanced FIGO stage, as well as between advanced FIGO stage and both lymph node and omental metastasis. Tumor size was associated with elevated CA-125 levels and bilateral tumors. Conclusion: Mucinous ovarian tumors in patients over 40 years old are more likely to be malignant, present at an advanced stage, and involve omental metastasis. Malignant histopathological results are associated with advanced FIGO stages, which in turn are linked to lymph node and omental metastasis. Tumors larger than 10 cm tend to have elevated CA-125 levels.

10aClinicopathological characteristics10aIndonesia10aMucinous ovarian tumors10aSingle center1 aNugraha, Bayu, Aditya1 aTjokroprawiro, Brahmana, Askandar uhttps://www.phcogj.com/article/2397