02481nas a2200313 4500008004100000245013900041210006900180260001700249300001400266490000700280520148700287653001601774653001701790653001901807653001401826653002001840653001701860100002201877700003401899700002701933700002301960700002701983700001902010700003102029700002302060700002102083700002302104856004002127 2024 eng d00aOverview of Cancer and Treatment Challenges: Harnessing the Anti-cancer Potential of Jasminum Sambac and its Nanoparticle Formulations0 aOverview of Cancer and Treatment Challenges Harnessing the Antic cOctober 2024 a1069-10760 v163 a

Cancer research strives to discover effective treatment strategies that target tumour cells while minimising the negative effects of traditional chemotherapy. Studies conducted on plant-based leads have yielded promising therapeutic activities, prompting researchers to remain vigilant in exploring further plant-based studies. Research has shown that phytochemicals found in the roots, leaves, and flowers of Jasminum sambac (J.sambac) have demonstrated various active functions, including anti-inflammatory, antimicrobial, immunomodulatory, and anxiolytic effects. The progress made in nanoparticle drug delivery systems for cancer treatment is noteworthy as it allows for higher doses of medication to be delivered directly to cancer cells while minimising the negative impact on healthy cells. Various reports showcase the nanoparticle synthesis of J.sambac for screening multiple diseases. This review provides an overview of cancer and the challenges of available treatments while exploring the potential of J.sambac for its anticancer, cytotoxic, and antioxidant properties. Furthermore, it sheds light on the recent advances made in nanoparticle formulations of Jasminum sambac for cancer and other ailments. Disseminating these updates could encourage additional exploration into the potential anti-cancer properties of J.sambac and foster the development of nanoparticles for more effective cancer treatment.

10aAnti-cancer10aAnti-oxidant10aCancer therapy10aCytotoxic10aJasminum Sambac10aNanoparticle1 aNomier, Yousra.A.1 aMohanan, Anugeetha, Thacheril1 aEl-Dakroury, Walaa, A.1 aHassan, Dallin, A.1 aNithya, Sermugapandian1 aJabeen, Aamena1 aMohammed, Eman, Merghani A1 aZewail, Moataz, B.1 aAsaad, Gihan, F.1 aAbbady, Zeinah, Y. uhttps://www.phcogj.com/article/2385