02181nas a2200193   4500008004100000245015100041210006900192260001800261300001400279490000700293520150800300653003301808653003001841653001301871100003201884700000501916700002601921856004001947       2023                        eng d00aThe Effect of Hyperbaric Oxygen Therapy (HBOT) on the  Histopathological Lung Cells of Male White Wistar Rats Which are  Intoxicated with Methanol0 aEffect of Hyperbaric Oxygen Therapy HBOT on the Histopathologica  cDecember 2023  a1202-12060 v153 a<p class="rtejustify">Methanol is a liquid that has the characteristics of being light, very easy to evaporate, colorless, flammable, toxic, and has a very distinctive odor like ethanol but lighter. The World Health Organization (WHO) globally states that 320,000 people die every year due to methanol poisoning in the age range of around 15 years to 29 years. Usually, symptoms of poisoning caused by methanol appear within 30 minutes to 2 hours. Based on the phenomenon that occurred, the author wanted to find out more about the effect of HBOT administration on the histopathological appearance of lung cells in mice intoxicated with methanol. This study used 30 male white wistar rat lung samples aged 2 to 3 months weighing around 150 grams to 250 grams, divided into three groups, namely the control group, treatment group I, and treatment group II. The control group was not given methanol treatment and hyperbaric oxygen therapy (HBOT). Treatment group I was given methanol for 14 days without hyperbaric oxygen therapy. Meanwhile, the treatment group was given methanol for 14 days and then given hyperbaric therapy for 10 days. The results show p&lt;0.0006, which means the data is significant and there are differences between groups. The results of this study can be concluded that administering hyperbaric oxygen therapy to rats intoxicated with methanol had a statistically significant improvement effect on the alveolar membrane, alveolar lumen, and connections between the alveoli.</p>
10aHistopathological Lung Cells10aHyperbaric Oxygen Therapy10aMethanol1 aPratiknya, Djatiwidodo, Edi1 a1 aBintoro, Ariyo, Sakso  uhttps://www.phcogj.com/article/2186