02498nas a2200289 4500008004100000024000700041245007600048210006900124260001400193300001200207490000700219520153900226653001801765653002501783653001801808653001801826100003901844700003501883700003301918700003601951700003501987700003502022700003902057700003802096700003402134856004002168 2023 eng d a3100aEffects of Melissa officinalis essential oil on state and trait anxiety0 aEffects of Melissa officinalis essential oil on state and trait  cJune 2023 a454-4600 v153 a

Introduction: Essential oils are complex substances used extensively in aromatherapy and phytotherapy, some of them as anxiety and stress-relieving agents. In order to evaluate the effects of Melissa officinalis essential oil on state and trait anxiety, this study was conducted. Methods: The essential oil was extracted by steam distillation and the chemical composition was investigated by Gas chromatographymass spectrometry (GC–MS). In addition, a Quasi experimental study with measures at pretest-posttest was conducted, where 58 participants were divided into two groups, a waiting-list (WL) control group, and an experimental group (EG)treated with aromatherapy based on Melissa officinalis essential oil. The anxiety index was evaluated by State-Trait Anxiety Inventory (STAI). Measures were taken at two times: pretest and posttest. Results: The chemical analysis showed that β-cubebene (26.3%), β-caryophyllene (25.4%) and geranial (12.5%) were de main components. Both state and trait anxiety levels decreased in the experimental group during the posttest phase; however, only state anxiety demonstrated statistically significant differences (p<0.05). A moderate size effect was found for state anxiety (d = 0.799; g= 0.797) with 1-β=0.803; but none for trait anxiety. Conclusion: Melissa officinalis essential oil was moderately effective on state anxiety but has no effect on trait anxiety.

10aEssential oil10aMelissa officinalis.10aState anxiety10aTrait anxiety1 aAlvarado-García, Paul, Alan Arkin1 aSoto-Vásquez, Marilú, Roxana1 aGomez, Francisco, Mercedes I1 aRodríguez, Natalia, Mavila Guz1 ade Guzmán, Yolanda, Elizabeth1 aJara-Aguilar, Demetrio, Rafael1 aRengifo-Penadillos, Roger, Antonio1 aGavidia-Valencia, José, Gilberto1 aAlfaro-Beltrán, Iris, Melina uhttps://www.phcogj.com/article/2057