02549nas a2200265   4500008004100000024000600041245015600047210006900203260001800272300001200290490000700302520170700309653001502016653001902031653002402050653002302074653001802097100000502115700002402120700002402144700001902168700002802187700002802215856004002243       2022                        eng d  a300aEffect of Bajakah Tea Extract (Spatholobus littoralis Hassk) on High Density Lipoprotein, Triglyceride and Total Cholesterol Levels in Male Wistar Rats0 aEffect of Bajakah Tea Extract Spatholobus littoralis Hassk on Hi  cDecember 2022  a687-6910 v143 a<p class="rtejustify">Hyperlipidemia is the high concentrations of low-density lipoprotein, cholesterol, and triglycerides in the blood. Furthermore, hyperlipidemia has a risk factor for cardiovascular complications through atherosclerosis that triggers coronary heart disease (CHD). <em>Spatholobus littoralis</em> Hassk known as Bajakah tea is a plant with high antioxidant content and acts as an HMG-CoA reductase inhibitor to suppress lipid metabolism disorders, increase HDL levels, and reduce triglycerides and total cholesterol. Experimental and posttest control group design methods were used to obtain 24 male Wistar rats. Furthermore, the experimental animals were randomly divided into 4 groups, namely K1 (normal rats), K2 (hyperlipidemia rats), K3 (hyperlipidemic rats + pirated tea extract dose 9 mg/200gramBW/day), and K4 (hyperlipidemic rats + simvastatin dose 0.18 mg/200 gBW/day). The study was conducted at the Center for Food and Nutrition Studies Laboratory, Gajah Mada University, Yogyakarta. Data levels of HDL, triglycerides, and total cholesterol were analyzed using the One Way Anova test and LSD post hoc to determine between groups. The results showed that an increase in triglyceride and total cholesterol and a decrease in HDL levels in the K2 group compared to the K1. Triglyceride and total cholesterol decreased in groups K3 and K4 compared to K2, and HDL levels increased in groups K3 and K4 compared to K2. Meanwhile, the results of the analysis obtained p value &lt;0.05. This study concluded that the administration of Bajakah tea extract at a dose of 9 mg/200gram BW/day for 14 days increase HDL, reduce triglyceride and total cholesterol levels (p&lt;0,05).</p>
10aHDL levels10aHyperlipidemia10aPirated tea extract10aTotal cholesterol.10aTriglycerides1 a1 aAulia, Andin, Putri1 aLiashari, Eka, Puji1 aHapsari, Happy1 aGibran, Syafrie, Sahrul1 aZulaikhah, Siti, Thomas  uhttps://www.phcogj.com/article/1898