01760nas a2200241 4500008004100000024000700041245014100048210006900189260001700258300001200275490000700287520102300294653000601317653003201323653002301355653000801378653000801386100001901394700001601413700002101429700002801450856004001478 2022 eng d a0700aPhytochemical Screening, Antioxidant Activity, and Anti- Inflammatory Potential of Rhinachantus nasutus (L.) Kurz Flower Ethanol Extract0 aPhytochemical Screening Antioxidant Activity and Anti Inflammato cOctober 2022 a521-5260 v143 a
Aims: The purpose of this study was to determine the content of the secondary metabolite compound in the flower extract of Rhinachantus nasutus (L.) Kurz (RnK); The potential of the extract as a radical scavenger of 2,2-diphenyl-1-picrylhydrazyl (DPPH); and its potential as an anti-inflammatory by inhibiting protein denaturation with bovine serum albumin (BSA). Results: Phytochemical screening results on the ethanolic extract of R. nasutus flowers revealed the presence of steroid glycosides, alkaloids, flavonoids, phenolics, and tannins. The extract has a strong ability to scavenge DPPH radicals with an IC50 value of 77.07 ± 0.05 mg/L. Besides that, the ethanol extract has very strong anti-inflammatory activity, with an IC50 value of 13.88 ± 0.2 mg/L. Conclusion: According to these findings, the ethanolic extract of R. nasutus flower can be used as an alternative anti-inflammatory drug.
10a210a2-diphenyl-1-picrylhydrazyl10aAnti-inflammatory.10aBSA10aRnK1 aIrawan, Candra1 aElya, Berna1 aHanafi, Muhammad1 aSaputri, Fadlina, Chany uhttps://www.phcogj.com/article/1864