02100nas a2200253 4500008004100000245007800041210006900119260001400188300001200202490000700214520130300221653002201524653001701546653001101563653001701574100002901591700002601620700003401646700003101680700003301711700003301744700002901777856004001806 2022 eng d00aPotential Anticancer Activity of Bioactive Compounds from Ipomoea batatas0 aPotential Anticancer Activity of Bioactive Compounds from Ipomoe cJune 2022 a650-6590 v143 a

Ipomoea batatas L. (Lam.) known as "sweet potato" is a plant species of great importance in the human diet due to the contribution of nutrients and also for its bioactive compounds that have various medicinal properties. Its anticancer activity is one of the properties that attract the attention of researchers in the study of plant species. This review aims to make a critical compilation of current information on research that evaluated the antitumor and antiproliferative activity of Ipomoea batatas. The studies included in this review show a diversity of bioactive compounds present in Ipomoea batatas such as phenolic compounds, anthocyanins, flavonoids, coumarins and sterols; also isolated compounds such as pectin, peptides and glycoproteins that can be related to their biological activity. It is concluded that there are positive results about Ipomoea batatas and its anticancer activity evaluated through in vitro and in vivo tests. In humans, safety and efficacy trials are still lacking to support its future use and allow drug development. Further research evaluating the safety and efficacy of reported bioactive compounds in Ipomoea batatas is important for the development of this promising area.

10aAntiproliferative10aAntitumoral.10aCancer10aSweet potato1 aSilva-Correa, Carmen, R.1 aHilario-Vargas, Julio1 aLa Torre, Víctor, E. Villarr1 aCalderón-Peña, Abhel, A.1 aGonzález-Siccha, Anabel, D.1 aAspajo-Villalaz, Cinthya, L.1 aCruzado-Razco, José, L. uhttps://www.phcogj.com/article/1816