01624nas a2200229 4500008004100000245009000041210006900131260001800200300001400218490000700232520097800239653002001217653001701237653000901254653002201263653001901285100000501304700001601309700002401325700000501349856004001354 2021 eng d00aThe Cytotoxicity Study of Lantana camara Linn Essential Oil on HeLa Cancer Cells Line0 aCytotoxicity Study of Lantana camara Linn Essential Oil on HeLa cNovember 2021 a1498-15010 v133 a
Lantana camara Linn (Verbenaceae) is a natural plant that thrives in tropical climates and is relatively easy to cultivate. In Indonesia, this plant is still often considered as a weed. When held, the unpleasant smell and sticky hand make people dislike this plant even though the flowers are diverse. The essential oil was extracted from the leaves of L. camara by hydrodistillation. This study aimed to see how cytotoxic L. camara essential oil was against HeLa carcinoma cells. This research aimed to discover if L. camara essential oil was cytotoxic to HeLa cancer cells. The GC-MS investigation of an essential oil recognized ten compounds; two main constituents of the oil were Caryophyllene (27.65%) and Germacrene D (23.01%). The essential oil showed cytotoxicity on HeLa cervical cancer cell lines. The cytotoxic effect of oil was determined using MTT, IC50 values were 44.86 μg/mL + 0.07
10aCervical cancer10aCytotoxicity10aHeLa10aHydrodistillation10aLantana camara1 a1 aHefni, Dira1 aWahyuni, Fatma, Sri1 a uhttps://www.phcogj.com/article/1689