01858nas a2200193 4500008004100000245012900041210006900170260001900239300001400258490000700272520122800279653001001507653002601517653002001543653001201563100002601575700002301601856004001624 2021 eng d00aAnalysis of Three-Dimensional Protein Structure of CBAVD in Indonesia as a Basis for Immunotherapy to Ensure Maternal Health0 aAnalysis of ThreeDimensional Protein Structure of CBAVD in Indon cSeptember 2021 a1282-12860 v133 a

Introduction: Congenital Bilateral Advance Vass Deferens (CBAVD) is a birth defect characterized by azoospermia. Determine the protein structure by laboratory research was relatively difficult. The threedimensional structure of proteins is computationally analyzed as an excellent and cost-effective alternative to analyzing protein characteristics. Objective: This study has an objective to identify the three-dimensional protein structure of CBAVD in Indonesia so that it can be used to obtain drugs and immunotherapy. Method: This study uses method of DNA extraction, PCR, and sequencing in collecting the data sample. The data was analyzed using using expasy software and Swiss prot. Result: The results of this study were found 6 CBAVD proteins, four to three dimensional CBAVD protein structures and 2 CBAVD proteins that have not been identified by the three dimensional protein structure. Further studies of CBAVD protein are needed, especially those related to protein isolation and crystallography. Conclusion: The three dimensional protein can be used as immunotherapy to ensure the maternal health.

10aCBAVD10aDimensional structure10aMaternal health10aProtein1 aMafruchati, Maslichah1 aMakuwira, Jonathan uhttps://www.phcogj.com/article/1659