02097nas a2200229 4500008004100000245010400041210006900145260001700214300001200231490000600243520142800249653001101677653001201688653001601700653002301716653001601739100002001755700002501775700002301800700000501823856003901828 2016 eng d00aAnti-Anemia Effect of Standardized Extract of Moringa Oleifera Lamk. Leaves on Aniline Induced Rats0 aAntiAnemia Effect of Standardized Extract of Moringa Oleifera La cJanuary 2016 a255-2580 v83 a

Background: The leaves of Moringa (Moringa oleifera Lamk.) have been empirically used as anti-anemia for pregnant woman. Objectives: In the present study, the effect of ethanolic extract of moringa leaves was evaluated on the hematology parameters (hemoglobin, red blood cell count, hematocrit), on aniline induced white female rats. Materials and Methods: Thirty female rats strain Sprague-Dawley were divided into six groups: normal, anemia and ferrous fumarate group, and three groups of Moringa leaves extract. All groups, except normal group, induced by aniline at dose 0.005 ml/ g bw intraperitonially. On fifth day, normal and anemia groups were given 0.5% CMC, ferrous fumarate group was given ferrous fumarate orally and three other groups were given Moringa leaves extract at doses 198 mg, 396 mg, and 792 mg/200 g bw until the eleventh day. Results: The results showed that as Moringa leaves extracts increased the level of hemoglobin, red blood cell count, hematocrit, and total iron content in blood. Moreover, Moringa leaves extract at dose 792 mg/200 g bw can improve red blood cell’s morphology and increased the level of hemoglobin and red blood cell count significantly (p<0.05). Conclusion: The ethanolic extract of Moringa leaves showed anti-anemia on aniline-induced rats.

10aAnemia10aAniline10aErythrocyte10aMoringa Oleifera L10aTotal Iron.1 aMun’im, Abdul1 aPuteri, Meidi, Utami1 aSari, Santi, Purna1 a uhttps://www.phcogj.com/article/142