02557nas a2200217 4500008004100000245019200041210006900233260001300302300001200315490000700327520180100334653002002135653002502155653001702180653002602197100002202223700001902245700001902264700001602283856004002299 2021 eng d00aThe Effect of Ethanol Extract of Moringa Leaf (Moringa oleifera Lam) Against the Activity and Capacity of Phagocytosis of Macrofag Cells and the Percentage of Leukosit Cells of White Mice0 aEffect of Ethanol Extract of Moringa Leaf Moringa oleifera Lam A cMay 2021 a706-7120 v133 a

Aim: This study aims to determine the activity, capacity of macrophage phagocytosis, and percentage of leukocyte cells of male mice treated with the ethanol extract of moringa leaves (Moringa oleifera Lam). Methods: Twenty male mice were divided into four equal groups. The extract was administered orally for seven days at a dose of 10; 30; 100 mg/kg; and 0.5% CMC Na suspension as a negative control. On the 8th day, the percentage of blood cell leukocytes in mice tail was calculated using a microscope. Suspension of Staphylococcus aureus was injected intraperitoneally. The peritoneal fluid was taken to figure the activity and capacity of macrophage cell phagocytosis. The activity and capacity of macrophage cells are calculated using a microscope. The data were statistically analyzed by the one-way variance analysis (ANOVA) method and Duncan test. Results: The results showed that giving oral ethanol extract of Moringa leaves on male could increase macrophage activity and capacity, increasing dose, macrophage activity number, and capacity increased. The highest activity and capacity was achieved at a dose of 100 mg/kg. Moringa leaf extract can also increase the percentage of banded neutrophil, lymphocytes, eosinophil cells and decrease the percentage of neutrophil cell segments and monocytes from male white mice. The highest percentage of banded neutrophil, lymphocytes, eosinophils, and reductions in the percentage of neutrophil cell segments, monocytes present at doses of 100 mg/kg. Conclusion: From the result, it can conclude that ethaol extract of Moringa Leaf can increase the activity and capacity of macrophages and percentage of neutrophils.

10amacrophage cell10aMoringa oleifera Lam10aPhagocytosis10aStaphylococcus aureus1 aHusni, Elidahanum1 aBadriyya, Elsa1 aPutri, Luqyana1 aAldi, Yufri uhttps://www.phcogj.com/article/1416