02061nas a2200241 4500008004100000245012200041210006900163260001900232300001400251490000700265520131700272653001601589653001701605653001501622653002301637653001201660100002601672700002101698700002301719700002001742700001701762856004001779 2020 eng d00aPhytochemical and Antioxidant Evaluation of the Flavonoids and Tannins from Synadenium grantii Hook f, (Ephorbiaceae)0 aPhytochemical and Antioxidant Evaluation of the Flavonoids and T cSeptember 2020 a1421-14280 v123 a

Background: The methanol extract (MeE) of the aerial parts from Synadenium grantii Hook f, (Ephorbiaceae) has more Polyphenols and used to treat several diseases. Objective: The aim of this study is isolation, purification and identification of Polyphenols that showed good antioxidant activity. Materials and Methods: In the present study, purification of the MeOH-H2O extract (70:30) from the air-dried aerial parts of S. grantii resulted by different chromatographic tools. The antioxidant activities were evaluated for the examined compounds by several methods using DPPH, Reducing power, ABTS and FRAP assays. Results: A total of 14 compounds were isolated from this plant species for the first time. The results obtained showed that all the examined compounds possess remarkable antioxidant activity through all assays especially compounds 2 and 4 where they showed the highest antioxidant activity among the other compounds and very close to the results of the standard compound BHA. Conclusion: The compounds examined have exhibited antioxidant activity with promising value as natural source antioxidant drugs.

10aAntioxidant10aEphorbiaceae10aFlavonoids10aSynadenium grantii10aTannins1 aElkarim, Asmaa, S Abd1 aAbdelaziz, Sahar1 aAttia, Hany, Gouda1 aTaie, Hanan, AA1 aMonir, Rafik uhttps://www.phcogj.com/article/1262