02249nas a2200193 4500008004100000245019100041210006900232260001300301300001300314490000700327520153800334653001401872653003101886653001501917100002901932700002801961700002601989856004002015 2020 eng d00aPharmacognostical Investigations of Hedysarum Caucasicum Bieb. (Fabaceae) - An Ethnomedicinal Plant of Northern Caucasus, Russia, Determination of Mangiferin and Antibacterial Potentials0 aPharmacognostical Investigations of Hedysarum Caucasicum Bieb Fa cMay 2020 a510-518 0 v123 a

The main active component of members of the genus Hedysarum is xanthone C-glycoside - mangiferin which was found in the above-ground part of 17 species of Hedysarum. Mangiferin is contained in plants of the genus Hedysarum can serve as a chemotaxonomic marker of this genus, it has antiviral activity against DNA-containing viruses: Herpes simplex virus, Varicella zoster, Cytomegaloviruses, also has immunostimulatory properties (stimulates cellular and humoral immunity). We have prepared the morphological and anatomical studying, phytochemical research availability of tannines, flavonoids, xanthones, the free organic acids, the sugars and amino acids among which in the significant amount glutamic acid, aspartic acid and an arginine collect is established. The maintenance of the sum of xanthones made 7.12%. As a result of a research of amino-acid structure of a grass of Hedysarum caucasicum Bieb. presence at the significant amount of glutamic acid (13.58 g/kg), aspartic acid (13.61 g/kg), an arginine (14.99 g/kg) is revealed. In a grass of Hedysarum caucasicum Bieb. The quantitative maintenance of the sum of xanthones in terms of a specific indicator of a mangiferin is established. The technology of receiving a liquid extract by means of 80% of ethanol is developed, standardization is carried out it. It is established that extract of Hedysarum caucasicum Bieb. shows the antimicrobial activity concerning Shigella sonnei, Bacillus subtilis and B.anthracoides.

10aHedysarum10aHedysarum caucasicum Bieb.10aMangiferin1 aК, Serebryanaya, Fatima1 aR, Imachueva, Djavgarat1 aA, Guseynova, Ziyarat uhttps://www.phcogj.com/article/1159