02174nas a2200229 4500008004100000245012800041210006900169260001300238300001200251490000700263520149500270653001201765653001701777653002101794653000801815653001901823100001901842700000501861700002101866700001701887856004001904 2020 eng d00aChemometric Analysis of Arbutin Derivatives from Paederia foetida and Vitis vinifera with Fourier Transform Infrared (FTIR)0 aChemometric Analysis of Arbutin Derivatives from Paederia foetid cMay 2020 a436-4410 v123 a

Introduction: Paederia foetida and Vitis vinifera were reported to have antioxidant activities due to their polyphenolic phytochemical contents. Arbutin may be included as active compounds in the plants. The chemometric analysis is used to identify the similarity of functional groups found in arbutin and that are in Paederia foetida and Vitis vinifera. Materials and Method: The ethanol extracts of Paderia foetida and Vitis vinifera were subjected to compound partition and characterization. Then a liquid-liquid partition is carried out using n-hexan and water solvents, followed by ethyl acetate and water partitions. This procedure is carried out continuously until the top layer is cleared. Partitioned compounds were analyzed using FTIR spectroscopy to identify functional groups. Furthermore, it was analyzed using the chemometric method (Principal Component Analysis and Cluster Analysis). Results: From the results of FTIR spectroscopy, functional groups in Paederia foetida and Vitis vinifera were identical to functional groups found in arbutin. PCA Analysis was achieved using principal component accounting an eigenvelue about 99,3 % of the total variance. Conclusions: CA analysis showed that compounds in Paederia foetida (Euclidean distance 0.537) and Vitis Vinifera (Euclidean distance 1.157) may be similar with arbutin.

10aArbutin10aChemometrics10aPaederia foetida10aPCA10aVitis vinifera1 aRifai, Yusnita1 a1 aDjabir, Yulia, Y1 aAlam, Gemini uhttps://www.phcogj.com/article/1129