02566nas a2200241 4500008004100000245016000041210006900201260001500270300001200285490000700297520176900304653001502073653001402088653001502102653002002117653002902137100002102166700002002187700002002207700002902227700002802256856004002284 2020 eng d00aDetermination of Total Flavonoid Levels of Ethanol Extract Sesewanua Leaf (Clerodendrum Fragrans Wild) With Maceration Method Using UV-Vis Spectrofotometry0 aDetermination of Total Flavonoid Levels of Ethanol Extract Sesew cMarch 2020 a356-3600 v123 a

Introduction: Sesewanuwa (Clerodendrum fragrans Wild) is one of the plants with abundant flavonoid content in the leaves. The characteristic flavonoids with the two benzene ring groups cause the process of finding an appropriate extraction technique. Objective: This study aims to determine the total flavonoid levels of ethanol extract of sesewanuwa leaves obtained from maceration extraction methods. Method: This research was carried out by extracting the simplicia of sesewanuwa leaves by maceration method using 96% ethanol solvent. Comparison between the simplicia and the solvent used is 1:7, then the extract obtained was carried out with initial qualitative identification of flavonoids with simple reagents and the total flavonoid levels were determined using UV-Vis spectrophotometry. Results: The results showed that the ethanol extract of sesewanuwa leaves obtained by maceration extraction method in qualitative and quantitative tests contained flavonoids with quercetin standard with a total content of 13.47%.This research was carried out by extracting the simplicia of sesewanuwa leaves by maceration method using 96% ethanol solvent. Comparison between the simplicia and the solvent used is 1:7, then the extract obtained was carried out with initial qualitative identification of flavonoids with simple reagents and the total flavonoid levels were determined using UV-Vis spectrophotometry. Conclusion: The results showed that the ethanol extract of sesewanuwa leaves obtained by maceration extraction method in qualitative and quantitative tests contained flavonoids with quercetin standard with a total content of 13.47%.

10aMaceration10aQuercetin10aSesewanuwa10atotal flavonoid10aUV-Vis spectrophotometry1 aSapiun, Zulfiayu1 aPangalo, Paulus1 aImran, Arlan, K1 aWicita, Prisca, Safriani1 aDaud, Rizka, Puji Astut uhttps://www.phcogj.com/article/1122