02170nas a2200217 4500008004100000245014300041210006900184260001800253300001400271490000700285520146600292653002401758653001001782653002701792653001401819100001801833700001901851700002001870700002201890856004001912 2019 eng d00aChemical Constituents and Antifungal Activity of Leaf Essential Oil from Oreopanax ecuadorensis Seem. (Pumamaki), Endemic Plant of Ecuador0 aChemical Constituents and Antifungal Activity of Leaf Essential  cNovember 2019 a1544-15480 v113 a

Background: Oreopanax ecuadorensis Seem. is a plant from Ecuador, that is found in the Andean region of the country. The plant is commonly used in protective rituals, and as an antiflu, analgesic and disinfectant medicine. Aim: The research aims to extract and analyze the chemical composition and evaluation of its antifungal potential of the essential oil extracted from its leaves. Methods: steam distillation was used for the extraction of essential oil, the evaluation of its components was performed by GC/MS, and the antifungal evaluation by the disc diffusion method. Results: The essential oil was obtained with a yield of 0.05%. 33 compounds were detected of which 30 were identified, corresponding to 99.28%; the most abundant molecules were: thujene <α-> (36.63%), followed by bicyclogermacrene with (8.76%), pinene <β-> with (8.32%) and limonene with 5.15%. Three of the four strains evaluated were affected by the oil at concentrations of 1.25%, inhibiting its growth. The strains were: Trichophyton mentagrophytes, Trichophyton rubrum and Microsporum canis. Conclusion: The essential oil shows good antifungal activity, which could be less than 1.25%. In this way, this medicinal plant is valued by verifying ancestral knowledge in the use of medicinal plants by the Andean people of Ecuador.

10aAntifungal activity10aGC/MS10aOreopanax ecuadorensis10aPuma Maki1 aNoriega, Paco1 aVergara, Bryan1 aCarillo, Carlos1 aMosquera, Tatiana uhttps://www.phcogj.com/article/1035