@article {1708,
	title = {Role of Capsaicin in the Repair of Cellular Activity in Mice Liver},
	journal = {Pharmacognosy Journal},
	volume = {13},
	year = {2021},
	month = {December 2021},
	pages = {1573-1576},
	type = {Original Article},
	chapter = {1573},
	abstract = {<p class="rtejustify">This study aimed to determine the capsaicin efficacy on Kupffer cell, polymorphonuclear, stellate, and fibroblast cells in mice liver induced with aflatoxin B1. A total of 20 mice were used as sample, assigned into four group i.e. (T0) administered 0,5 ml of polyethylene glycol, (T1) administered 0,5 ml of capsaicin + 0,5 ml of polyethylene glycol, (T2) administered 0,1 ml of aflatoxin B1 + 0,5 ml of polyethylene glycol, (T3) administered 0,1 ml of aflatoxin B1 + 0,5 ml of capsaicin, respectively. All treatment were done for a month then followed by liver dissection for hematoxylin eosin staining. The differential cells counted then analyzed using ANOVA and Tukey multiple comparison test (p\&lt;0,05). The cell determination showed that Kupffer cell, polymorphonuclear, stellate, and fibroblast cells decreased significantly (p\&lt;0,05) in T3 group compared to T2 group. Meanwhile, the T1 group showed similar (p\&gt;0,05) with T0 group. It can be concluded that capsaicin has a potential effect to improve cellular activity in mice liver with aflatoxin B1 toxication.</p>
},
	keywords = {Aflatoxin B1, Animal, Capsaicin, Fibroblast., Kupffer cell, Stellate},
	doi = {10.5530/pj.2021.13.201},
	author = {Mohammad Sukmanadi and Mustofa Helmi Effendi and Faisal Fikri and Muhammad Thohawi Elziyad Purnama}
}
